YRC Public Data Repository - Protein Structure Prediction

Protein:	NDUS7_MOUSE
Organism:	Mus musculus
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDUS7_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|56606108, gi\|... - gi\|56606108\|ref\|NP_001008525.1\| NADH dehydrogenase (ubiquinone) Fe-S protein 7 [Rattus norvegicus], ...	288.0	[0..1]	[224..1]
gi\|39971881, gi\|... - gi\|39971881\|ref\|XP_367331.1\| hypothetical protein MG07256.4 [Magnaporthe grisea 70-15], gb\|EAA56901....	287.0	[0..6]	[224..864]
NDUS7_PONAB - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Pongo abelii GN=NDUFS7 PE=2 ... NDUS7_PONPY - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial precursor - Pongo pygmaeus (Ora...	282.0	[0..1]	[224..1]
gi\|84105526, gi\|... - gi\|8488995\|sp\|O75251\|NUKM_HUMAN NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial precurs...	282.0	[0..1]	[224..1]
NDUS7_PANTR - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Pan troglodytes GN=NDUFS7 PE...	280.0	[0..1]	[224..1]
NDUS7_PONPY - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Pongo pygmaeus GN=NDUFS7 PE=... gi\|111661828 - gi\|111661828\|gb\|ABH12164.1\| mitochondrial complex I subunit NDUFS7 [Gorilla gorilla] NDUS7_GORGO - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Gorilla gorilla gorilla GN=N...	279.0	[0..1]	[224..1]
gi\|109122788 - gi\|109122788\|ref\|XP_001117356.1\| PREDICTED: similar to NADH-ubiquinone oxidoreductase Fe-S protein 7...	278.0	[0..1]	[224..1]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALAAPGLL SVRILGLRTA QVQLRRVHQS VATEGPSPSP SPSLSSTQSA VSKAGAGAVV  60
   61 PKLSHLPRSR AEYVVTKLDD LINWARRSSL WPMTFGLACC AVEMMHMAAP RYDMDRFGVV 120
  121 FRASPRQADV MIVAGTLTNK MAPALRKVYD QMPEPRYVVS MGSCANGGGY YHYSYSVVRG 180
  181 CDRIVPVDIY VPGCPPTAEA LLYGILQLQR KIKREQKLKI WYRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.69897
Match:	2fug6
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	13.9361001493201	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	12.823760326196	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	12.8237449606378	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	12.2946357205778	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	11.5463682902166	bayes_pls_golite062009
oxidoreductase activity	6.65509281399906	bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity	3.12366321374445	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	2.30490418238429	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor	1.94254997143399	bayes_pls_golite062009
catalytic activity	1.41356903593784	bayes_pls_golite062009
iron-sulfur cluster binding	1.3943220140881	bayes_pls_golite062009
metal cluster binding	1.3943220140881	bayes_pls_golite062009
binding	1.17917653224043	bayes_pls_golite062009
ferredoxin hydrogenase activity	1.17664896715936	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	1.17664896715936	bayes_pls_golite062009
protein binding	0.548818495297466	bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors	0.100407685917506	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: