YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|6671622, gi\|1...
Organism:	Mus musculus
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6671622, gi|1....

Description	E-value	Query Range	Subject Range
PHB2_BOVIN - Prohibitin-2 OS=Bos taurus GN=PHB2 PE=2 SV=1	242.0	[0..1]	[298..1]
PHB2_RAT - Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=1 SV=1	242.0	[0..1]	[298..1]
gi\|53734337 - gb\|AAH84026.1\| Unknown (protein for MGC:98216) [Xenopus laevis] gi\|114643120 - gi\|114643120\|ref\|XP_508977.2\| PREDICTED: prohibitin 2 isoform 3 [Pan troglodytes] PHB2_MOUSE - Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1 gi\|123981810, gi... - gi\|157928262\|gb\|ABW03427.1\| prohibitin 2 [synthetic construct], gi\|123981810\|gb\|ABM82734.1\| prohibit... gi\|109095407 - gi\|109095407\|ref\|XP_001111957.1\| PREDICTED: similar to Prohibitin-2 (B-cell receptor-associated prot... PHB2 - prohibitin 2	241.0	[0..1]	[298..1]
gi\|55728600 - gi\|55728600\|emb\|CAH91041.1\| hypothetical protein [Pongo abelii] PHB2_PONAB - Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1	238.0	[0..1]	[298..1]
PHB2_XENTR - Prohibitin-2 OS=Xenopus tropicalis GN=phb2 PE=2 SV=1	237.0	[0..1]	[297..1]
gi\|148228072, gi... - gi\|49522786\|gb\|AAH74451.1\| MGC84728 protein [Xenopus laevis], gi\|148228072\|ref\|NP_001086302.1\| MGC84...	234.0	[0..1]	[297..1]
gi\|109095405 - gi\|109095405\|ref\|XP_001111851.1\| PREDICTED: similar to Prohibitin-2 (B-cell receptor-associated prot...	231.0	[0..1]	[298..1]
gi\|50757151 - gi\|50757151\|ref\|XP_415401.1\| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...	227.0	[0..3]	[286..390]

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Predicted Domain #1

Region A:
Residues: [1-64]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQNLKDLAG RLPAGPRGMG TALKLLLGAG AVAYGVRESV FTVEGGHRAI FFNRIGGVQQ  60
   61 DTIL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [65-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEFHFRIPWF QYPIIYDIRA RPRKISSPTG SKDLQMVNIS LRVLSRPNAQ ELPSMYQRLG  60
   61 LDYEERVLPS IVNEVLKSVV AKFNASQLIT QRAQVSLLIR RELTERAKDF SLILDDVAIT 120
  121 EL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	1winA
Description:	Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.10215477176861	bayes_pls_golite062009
protein binding	0.769979871341236	bayes_pls_golite062009
structural molecule activity	0.591437172549816	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [187-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG  60
   61 YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: