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View Structure Prediction Details

Protein: IL13_MOUSE
Organism: Mus musculus
Length: 131 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL13_MOUSE.

Description E-value Query
Range		 Subject
Range
gi|33088189 - gi|33088189|gb|AAP93198.1| interleukin 13 [Sigmodon hispidus]
 230.0 [0..1] [131..1]
IL13_RAT - Interleukin-13 OS=Rattus norvegicus GN=Il13 PE=2 SV=1
 223.0 [0..1] [129..1]
IL13_MACMU - Interleukin-13 OS=Macaca mulatta GN=IL13 PE=2 SV=1
 220.0 [0..1] [131..1]
gi|110559067 - gi|110559067|gb|ABG75889.1| IL13 [Macaca fascicularis]
 218.0 [0..1] [131..1]
gi|21617529 - gi|21617529|gb|AAM66721.1|AF518409_1 interleukin 13 [Meriones unguiculatus]
 213.0 [0..1] [124..1]
IL13_PIG - Interleukin-13 OS=Sus scrofa GN=IL13 PE=2 SV=1
 213.0 [0..1] [129..1]
IL13_CAMBA - Interleukin-13 OS=Camelus bactrianus GN=IL13 PE=2 SV=1
IL13_LAMGL - Interleukin-13 OS=Lama glama GN=IL13 PE=2 SV=1
 213.0 [0..1] [131..1]
IL13_CANLF - Interleukin-13 OS=Canis lupus familiaris GN=IL13 PE=2 SV=1
 208.0 [0..1] [131..1]
gi|1127548 - gi|1127548|gb|AAA83738.1| interleukin 13
 208.0 [0..1] [131..1]
gi|67944395 - gi|67944395|gb|AAY83833.1| interleukin-13 [Bubalus bubalis]
 207.0 [0..1] [131..1]

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Predicted Domain #1
Region A:
Residues: [1-131] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWVTAVLA LACLGGLAAP GPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD  60
   61 LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS 120
  121 YTKQLFRHGP F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1ga3A
Description: Interleukin-13 (IL-13)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 5.3304255990112 bayes_pls_golite062009
cytokine activity 5.22856893358132 bayes_pls_golite062009
growth factor activity 4.92105782010612 bayes_pls_golite062009
cytokine receptor binding 4.4791226814754 bayes_pls_golite062009
protein binding 3.26483713001551 bayes_pls_golite062009
hormone activity 2.52921243340076 bayes_pls_golite062009
binding 2.48265117231403 bayes_pls_golite062009
interleukin-10 receptor binding 2.21581243177298 bayes_pls_golite062009
interleukin-12 binding 1.970502825442 bayes_pls_golite062009
interleukin-13 receptor binding 1.49817347309677 bayes_pls_golite062009
interleukin-2 receptor binding 1.04202431319586 bayes_pls_golite062009
interleukin-12 beta subunit binding 0.905609556134391 bayes_pls_golite062009
interleukin-6 receptor binding 0.662779243177561 bayes_pls_golite062009
interleukin-27 binding 0.39282199030202 bayes_pls_golite062009
interferon-alpha/beta receptor binding 0.28794265715482 bayes_pls_golite062009
interleukin-12 receptor binding 0.218984052557791 bayes_pls_golite062009
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