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View Structure Prediction Details

Protein: IL19_MOUSE
Organism: Mus musculus
Length: 176 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL19_MOUSE.

Description E-value Query
Range
Subject
Range
gi|15266466, gi|... - gi|15266466|gb|AAK91776.1| interleukin 19 [Homo sapiens], gi|119613928|gb|EAW93522.1| interleukin 19...
219.0 [0..1] [176..39]
gi|114572230 - gi|114572230|ref|XP_001165088.1| PREDICTED: interleukin 19 isoform 1 [Pan troglodytes]
218.0 [0..1] [176..39]
gi|109497841, gi... - gi|109498595|ref|XP_001058779.1| PREDICTED: similar to interleukin 19 [Rattus norvegicus], gi|109497...
203.0 [0..1] [175..1]
IL10_HORSE - Interleukin-10 OS=Equus caballus GN=IL10 PE=2 SV=1
196.0 [0..7] [167..4]
gi|18025468, gi|... - gi|51518017|ref|YP_067941.1| BCRF1 [Macacine herpesvirus 4], gi|18025468|gb|AAK95412.1| BCRF1 [cerco...
193.0 [0..1] [167..7]
IL10_SAISC - Interleukin-10 OS=Saimiri sciureus GN=IL10 PE=2 SV=1
192.0 [0..10] [167..6]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTQCASTWL LGMTLILCSV HIYSLRRCLI SVDMRLIEKS FHEIKRAMQT KDTFKNVTIL  60
   61 SLENLRSIKP GDVCCMTNNL LTFYRDRVFQ DHQERSLEVL RRISSIANSF LCVQKSLERC 120
  121 QVHRQCNCSQ EATNATRIIH DNYNQLEVSS AALKSLGELN ILLAWIDRNH LETPAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.39794
Match: 1n1fA
Description: Interleukin-19
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 5.3304255990112 bayes_pls_golite062009
cytokine activity 4.52280271433847 bayes_pls_golite062009
cytokine receptor binding 3.77877275351612 bayes_pls_golite062009
growth factor activity 3.72884804690203 bayes_pls_golite062009
protein binding 3.26483713001551 bayes_pls_golite062009
binding 2.48265117231403 bayes_pls_golite062009
interleukin-10 receptor binding 2.03829634645987 bayes_pls_golite062009
hormone activity 1.36735241300603 bayes_pls_golite062009
catalytic activity 0.246169290135575 bayes_pls_golite062009
interleukin-6 receptor binding 0.0605673585279907 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle