YRC Public Data Repository - Protein Structure Prediction

Protein:	CRF_MOUSE
Organism:	Mus musculus
Length:	187 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRF_MOUSE.

Description	E-value	Query Range	Subject Range
CRF_RAT - Corticoliberin OS=Rattus norvegicus GN=Crh PE=1 SV=1	229.0	[0..1]	[187..1]
gi\|90077166 - gi\|90077166\|dbj\|BAE88263.1\| unnamed protein product [Macaca fascicularis] gi\|109086578 - gi\|109086578\|ref\|XP_001094433.1\| PREDICTED: similar to Corticoliberin precursor (Corticotropin-relea...	222.0	[0..1]	[187..1]
gi\|60655145 - gi\|60655145\|gb\|AAX32136.1\| corticotropin releasing hormone [synthetic construct] gi\|114620343 - gi\|114620343\|ref\|XP_519792.2\| PREDICTED: similar to corticotropin releasing factor [Pan troglodytes] HGNC:2355\|MIM:12... - releasing hormone, releasing hormone CRH - corticotropin releasing hormone	219.0	[0..1]	[187..1]
CRF_CANLF - Corticoliberin OS=Canis lupus familiaris GN=CRH PE=2 SV=2	218.0	[0..1]	[187..1]
CRF_PIG - Corticoliberin precursor - Sus scrofa (Pig)	217.0	[0..1]	[187..1]
gi\|185134351, gi... - gi\|34391389\|gb\|AAL09823.1\| corticotropin-releasing factor precursor [Oncorhynchus mykiss], gi\|333399...	216.0	[0..1]	[187..1]
gi\|29691154 - gi\|29691154\|gb\|AAO89527.1\| corticotropin-releasing factor [Salvelinus alpinus]	208.0	[0..2]	[187..1]
CRF_CARAU - Corticoliberin OS=Carassius auratus GN=crh PE=1 SV=1	205.0	[0..1]	[187..1]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLRLLVSAG MLLVALSSCL PCRALLSRGS VPRAPRAPQP LNFLQPEQPQ QPQPVLIRMG  60
   61 EEYFLRLGNL NRSPAARLSP NSTPLTAGRG SRPSHDQAAA NFFRVLLQQL QMPQRSLDSR 120
  121 AEPAERGAED ALGGHQGALE RERRSEEPPI SLDLTFHLLR EVLEMARAEQ LAQQAHSNRK 180
  181 LMEIIGK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits