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View Structure Prediction Details

Protein: gi|12850634, gi|...
Organism: Mus musculus
Length: 291 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12850634, gi|....

Description E-value Query
Range
Subject
Range
IMP4_RAT - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Rattus norvegicus GN=Imp4 PE=2 SV=1
IMP4_MOUSE - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Mus musculus GN=Imp4 PE=2 SV=1
345.0 [0..12] [291..12]
gi|22902285 - gi|22902285|gb|AAH37602.1| Imp4 protein [Mus musculus]
345.0 [0..12] [291..17]
gi|109104608 - gi|109104608|ref|XP_001093227.1| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, h...
343.0 [0..12] [291..12]
gi|55729975 - gi|55729975|emb|CAH91713.1| hypothetical protein [Pongo abelii]
gi|55729975|emb|... - hypothetical protein [Pongo pygmaeus]
343.0 [0..12] [291..11]
IMP4 - IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
gi|124000169, gi... - gi|157929232|gb|ABW03901.1| IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) [synthetic c...
341.0 [0..12] [291..12]
gi|73993566 - gi|73993566|ref|XP_534545.2| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, homol...
340.0 [0..17] [291..65]
gi|66514411 - gi|66514411|ref|XP_395323.2| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, homol...
339.0 [0..1] [291..1]
IMP4_BOVIN - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Bos taurus GN=IMP4 PE=2 SV=1
338.0 [0..12] [291..12]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRREARLRR EYLYRKAREE AHGSVQEKKE RVKRALEENQ LIPTELRREA LALQGSLEFD  60
   61 DAGGEGVTSH VDDEYRWAGV E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.685 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.639 N/A N/A a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.633 N/A N/A a.2.7 tRNA-binding arm
View Download 0.608 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.607 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac

Predicted Domain #2
Region A:
Residues: [82-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPKVMITTSR DPSSRLKMFA KELKLVFPGA QRMNRGRHEV GALVRACKAN GVTDLLVVHE  60
   61 HRGTPVGLIV SHLPFGPTAY FTLCNVVMRH DI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 2cxhA
Description: Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aminoacyl-tRNA ligase activity 3.58650371779212 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.58624422951947 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.58624422951947 bayes_pls_golite062009
ligase activity 2.71574082295198 bayes_pls_golite062009
proline-tRNA ligase activity 2.35871952544841 bayes_pls_golite062009
binding 1.73857064375258 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.358563180490135 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [174-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDLGTMSEAK PHLITHGFSS RLGKRVSDIL RYLFPVPKDD SHRVITFANQ DDYISFRHHV  60
   61 YKKTDHRNVE LTEVGPRFEL KLYMIRLGTL EQEATADVEW RWHPYTNTAR KRVFLSAE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.74
Match: 2cxhA
Description: Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle