YRC Public Data Repository - Protein Structure Prediction

Protein:	ISCA1_MOUSE
Organism:	Mus musculus
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISCA1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|73946570 - gi\|73946570\|ref\|XP_849435.1\| PREDICTED: similar to HESB like domain containing 2 [Canis familiaris]	176.0	[0..1]	[129..132]
gi\|94394826, gi\|... - gi\|94395869\|ref\|XP_992569.1\| PREDICTED: similar to HESB like domain containing 2 [Mus musculus], gi\|...	176.0	[0..1]	[129..43]
gi\|21740005 - gi\|21740005\|emb\|CAD39021.1\| hypothetical protein [Homo sapiens]	174.0	[0..1]	[129..21]
ISCA1_RAT - Iron-sulfur cluster assembly 1 homolog, mitochondrial OS=Rattus norvegicus GN=Isca1 PE=2 SV=1	173.0	[0..1]	[129..1]
gi\|37197683, gi\|... - gi\|37678941\|ref\|NP_933550.1\| hypothetical protein VV0757 [Vibrio vulnificus YJ016], gi\|37197683\|dbj\|...	172.0	[0..23]	[129..1]
gi\|126208405, gi... - gi\|126208405\|ref\|YP_001053630.1\| iron-binding protein IscA [Actinobacillus pleuropneumoniae L20], gi... gi\|190150256, gi... - gi\|190150256\|ref\|YP_001968781.1\| iron-binding protein IscA [Actinobacillus pleuropneumoniae serovar ... gi\|165976348, gi... - gi\|165976348\|ref\|YP_001651941.1\| iron-binding protein [Actinobacillus pleuropneumoniae serovar 3 str... gi\|32034039 - gi\|32034039\|ref\|ZP_00134283.1\| COG0316: Uncharacterized conserved protein [Actinobacillus pleuropneu...	172.0	[0..23]	[129..1]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLVRATV RAVSKRKLQP TRAALTLTPS AVNKIKQLLK DKPEHVGLKV GVRTRGCNGL  60
   61 SYSLEYTKTK GDSDEEVIQD GVRVFIEKKA QLTLLGTEMD YVEDKLSSEF VFNNPNIKGT 120
  121 CGCGESFHV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.522879
Match:	1s98A
Description:	E.coli IscA crystal structure to 2.3 A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2 iron, 2 sulfur cluster binding	1.80248983815833	bayes_pls_golite062009
iron-sulfur cluster binding	1.47577968990921	bayes_pls_golite062009
metal cluster binding	1.47577968990921	bayes_pls_golite062009
binding	0.0602586837339399	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: