YRC Public Data Repository - Protein Structure Prediction

Protein:	LIN37_MOUSE
Organism:	Mus musculus
Length:	246 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIN37_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109461669, gi... - gi\|27731069\|ref\|XP_214898.1\| PREDICTED: similar to Myb-interacting protein 40 CG15119-PA [Rattus nor...	411.0	[0..1]	[246..1]
gi\|73948465 - gi\|73948465\|ref\|XP_541689.2\| PREDICTED: similar to CG15119-PA [Canis familiaris]	392.0	[0..1]	[246..91]
gi\|114677061 - gi\|114677061\|ref\|XP_001159251.1\| PREDICTED: similar to Protein F25965 [Pan troglodytes]	390.0	[0..1]	[246..70]
LIN37 - lin-37 homolog (C. elegans)	388.0	[0..1]	[246..1]
gi\|109124394 - gi\|109124394\|ref\|XP_001098101.1\| PREDICTED: similar to Myb-interacting protein 40 CG15119-PA isoform...	387.0	[0..1]	[246..1]
gi\|15488831 - gi\|15488831\|gb\|AAH13546.1\| Lin37 protein [Mus musculus]	382.0	[0..15]	[246..1]
LIN37_BOVIN - Protein lin-37 homolog OS=Bos taurus GN=LIN37 PE=2 SV=1	375.0	[0..1]	[246..1]
gi\|56118941, gi\|... - gi\|56118941\|ref\|NP_001008000.1\| MGC79463 protein [Xenopus (Silurana) tropicalis], gi\|51703349\|gb\|AAH...	233.0	[0..1]	[246..1]
gi\|62205229, gi\|... - gi\|62955743\|ref\|NP_001017888.1\| lin-37 homolog [Danio rerio], gi\|62205229\|gb\|AAH92956.1\| Lin-37 homo...	231.0	[0..1]	[245..1]

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Predicted Domain #1

Region A:
Residues: [1-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPVKVKVEK SEMEMAKARN QLDAVLQCLL EKSHMDRERL DEEAGKTPLD THNKDCSIAA  60
   61 TGKRPSARFP HQRRKKRREM DDGLAE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.499	a.144.1	PABC (PABP) domain
View	Download	0.358	a.76.1	Iron-dependent represor protein, dimerization domain
View	Download	0.343	d.79.2	Tubulin/Dihydroxyacetone kinase C-terminal domain
View	Download	0.315	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View	Download	0.303	a.24.13	Domain of the SRP/SRP receptor G-proteins

Predicted Domain #2

Region A:
Residues: [87-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGPQRSNTYV IKLFDRSVDL AQFSENTPLY PICRAWMRNS PTVRERERSP GSPLPPLPED  60
   61 GEGSEVINSK NRDVYKLPPP TAPGPLGDAC RSRIPSPLQP ETEGTPDDEP SEPEPSPSTL 120
  121 IYRNMQRWKR IRQRWKEASH RNQLRYSESM KILREMYDRQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.336	N/A	N/A	c.2.1	NAD(P)-binding Rossmann-fold domains
View	Download	0.281	N/A	N/A	a.19.1	Fertilization protein
View	Download	0.258	N/A	N/A	c.2.1	NAD(P)-binding Rossmann-fold domains

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits