YRC Public Data Repository - Protein Structure Prediction

Protein:	ITPA_MOUSE
Organism:	Mus musculus
Length:	198 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ITPA_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|12842364 - gi\|12842364\|dbj\|BAB25571.1\| unnamed protein product [Mus musculus]	293.0	[0..1]	[198..1]
ITPA_RAT - Inosine triphosphate pyrophosphatase OS=Rattus norvegicus GN=Itpa PE=3 SV=1	288.0	[0..1]	[198..1]
gi\|114680669 - gi\|114680669\|ref\|XP_001161047.1\| PREDICTED: inosine triphosphatase isoform 3 [Pan troglodytes]	275.0	[0..1]	[194..1]
gi\|114794739 - gi\|114794739\|pdb\|2I5D\|A Chain A, Crystal Structure Of Human Inosine Triphosphate Pyrophosphatase	275.0	[0..1]	[194..4]
gi\|109092716 - gi\|109092716\|ref\|XP_001115179.1\| PREDICTED: similar to inosine triphosphatase isoform a isoform 2 [M...	273.0	[0..1]	[196..1]
ITPA_BOVIN - Inosine triphosphate pyrophosphatase OS=Bos taurus GN=ITPA PE=2 SV=1	273.0	[0..1]	[197..1]

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Predicted Domain #1

Region A:
Residues: [1-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASLVGKKI VFVTGNAKKL EEVIQILGDN FPCTLEAQKI DLPEYQGEPD EISIQKCREA  60
   61 ARQVQGPVLV EDTCLCFNAL GGLPGPYIKW FLQKLKPEGL HQLLAGFEDK SAYALCTFAL 120
  121 STGDPSQPVL LFRGQTSGQI VMPRGSRDFG WDPCFQPDGY EQTYAEMPKS EKNTISHRFR 180
  181 ALHKLQEYFS VAAGAGDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.30103
Match:	2i5dA
Description:	No description for 2i5dA was found.

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphate diphosphatase activity	2.4486133651528	bayes_pls_golite062009
binding	1.2828743465361	bayes_pls_golite062009
protein binding	0.121994365068808	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: