YRC Public Data Repository - Protein Structure Prediction

Protein:	MED10_MOUSE
Organism:	Mus musculus
Length:	135 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED10_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|50736031 - gi\|50736031\|ref\|XP_419024.1\| PREDICTED: similar to DNA segment, Chr 13, Wayne State University 50, e...	218.0	[0..1]	[134..74]
ENSCJAT00000016867 - null MED10_PONPY - Mediator of RNA polymerase II transcription subunit 10 - Pongo pygmaeus (Orangutan) MED10 - mediator complex subunit 10 gi\|114598920 - gi\|114598920\|ref\|XP_001143506.1\| PREDICTED: mediator of RNA polymerase II transcription, subunit 10 ... MED10_PONAB - Mediator of RNA polymerase II transcription subunit 10 OS=Pongo abelii GN=MED10 PE=2 SV=1 MED10_BOVIN - Mediator of RNA polymerase II transcription subunit 10 OS=Bos taurus GN=MED10 PE=2 SV=1	213.0	[0..1]	[135..1]
gi\|74224290 - gi\|74224290\|dbj\|BAE33733.1\| unnamed protein product [Mus musculus]	212.0	[0..1]	[135..1]
MED10_XENTR - Mediator of RNA polymerase II transcription subunit 10 OS=Xenopus tropicalis GN=med10 PE=2 SV=1	210.0	[0..1]	[135..1]
CCDS34134.1_1 - null gi\|109076692 - gi\|109076692\|ref\|XP_001082923.1\| PREDICTED: similar to Mediator complex subunit 10 CG5057-PA [Macaca...	209.0	[0..1]	[135..1]
MED10_XENLA - Mediator of RNA polymerase II transcription subunit 10 OS=Xenopus laevis GN=med10 PE=2 SV=1	209.0	[0..1]	[135..1]
MED10_MACFA - Mediator of RNA polymerase II transcription subunit 10 OS=Macaca fascicularis GN=MED10 PE=2 SV=1	208.0	[0..1]	[135..1]
gi\|62202758, gi\|... - gi\|62955367\|ref\|NP_001017699.1\| transcriptional mediator complex subunit 10 [Danio rerio], gi\|622027...	196.0	[0..1]	[135..1]
gi\|47229507 - gi\|47229507\|emb\|CAF99495.1\| unnamed protein product [Tetraodon nigroviridis]	187.0	[0..1]	[131..1]

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Predicted Domain #1

Region A:
Residues: [1-135]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEKFDHLEE HLEKFVENIR QLGIIVSDFQ PSSQAGLSQK LNFIVTGLQD IDKCRQQLHD  60
   61 ITVPLEVFEY IDQGRNPQLY TKECLERALA KNEQVKGKID TMKKFKSLLI QELSKVFPED 120
  121 MAKYRSIRGE DHPPS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.537	a.74.1	Cyclin-like
View	Download	0.517	d.52.7	Ribosome-binding factor A, RbfA
View	Download	0.457	d.227.1	OsmC-like
View	Download	0.445	a.24.18	Description not found.
View	Download	0.444	a.118.8	TPR-like
View	Download	0.444	a.118.8	TPR-like
View	Download	0.438	d.232.1	Mago nashi protein
View	Download	0.429	d.52.7	Ribosome-binding factor A, RbfA
View	Download	0.407	a.1.1	Globin-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits