YRC Public Data Repository - Protein Structure Prediction

Protein:	IL23A_MOUSE
Organism:	Mus musculus
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL23A_MOUSE.

Description	E-value	Query Range	Subject Range
IL23A_RAT - Interleukin-23 subunit alpha OS=Rattus norvegicus GN=Il23a PE=2 SV=1	359.0	[0..1]	[196..1]
gi\|42542687 - gi\|42542687\|gb\|AAH66267.1\| Interleukin 23, alpha subunit p19 [Homo sapiens]	338.0	[0..1]	[189..1]
gi\|109097297 - gi\|109097297\|ref\|XP_001115026.1\| PREDICTED: similar to interleukin 23, alpha subunit p19 precursor [... CCDS8916.1_1 - null	333.0	[0..1]	[189..1]
gi\|30144669 - gi\|30144669\|gb\|AAP15041.1\| interleukin-23a subunit p19 [Peromyscus maniculatus]	332.0	[0..1]	[184..1]
IL23A_HORSE - Interleukin-23 subunit alpha OS=Equus caballus GN=IL23A PE=3 SV=1	324.0	[0..1]	[189..1]
IL23A_PIG - Interleukin-23 subunit alpha OS=Sus scrofa GN=IL23A PE=3 SV=1	307.0	[0..1]	[190..1]
gi\|73968375 - gi\|73968375\|ref\|XP_538231.2\| PREDICTED: similar to interleukin 23, alpha subunit p19 precursor [Cani...	306.0	[0..1]	[189..1]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDCRAVIML WLLPWVTQGL AVPRSSSPDW AQCQQLSRNL CMLAWNAHAP AGHMNLLREE  60
   61 EDEETKNNVP RIQCEDGCDP QGLKDNSQFC LQRIRQGLAF YKHLLDSDIF KGEPALLPDS 120
  121 PMEQLHTSLL GLSQLLQPED HPRETQQMPS LSSSQQWQRP LLRSKILRSL QAFLAIAARV 180
  181 FAHGAATLTE PLVPTA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.49
Match:	1i1rB
Description:	Interleukin-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	3.40445451697915	bayes_pls_golite062009
binding	3.26381717534533	bayes_pls_golite062009
receptor binding	3.08282919778062	bayes_pls_golite062009
cytokine activity	1.52941204965521	bayes_pls_golite062009
cytokine receptor binding	1.5192399751028	bayes_pls_golite062009
growth factor activity	1.26647258046752	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: