YRC Public Data Repository - Protein Structure Prediction

Protein:	LIN7B_MOUSE
Organism:	Mus musculus
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIN7B_MOUSE.

Description	E-value	Query Range	Subject Range
LIN7B_RAT - Protein lin-7 homolog B OS=Rattus norvegicus GN=Lin7b PE=1 SV=1	181.0	[0..1]	[207..1]
gi\|109125454 - gi\|109125454\|ref\|XP_001114658.1\| PREDICTED: similar to lin-7 homolog B isoform 2 [Macaca mulatta] LIN7B - lin-7 homolog B (C. elegans) gi\|73947126 - gi\|73947126\|ref\|XP_851922.1\| PREDICTED: similar to lin-7 homolog B isoform 2 [Canis familiaris]	180.0	[0..1]	[207..1]
gi\|109125456 - gi\|109125456\|ref\|XP_001114636.1\| PREDICTED: similar to lin-7 homolog B isoform 1 [Macaca mulatta]	175.0	[0..1]	[201..1]
LIN7B_BOVIN - Protein lin-7 homolog B OS=Bos taurus GN=LIN7B PE=2 SV=1	174.0	[0..1]	[201..1]
gi\|73947124 - gi\|73947124\|ref\|XP_533623.2\| PREDICTED: similar to lin-7 homolog B isoform 1 [Canis familiaris]	169.0	[0..1]	[207..1]
gi\|114678227 - gi\|114678227\|ref\|XP_001156271.1\| PREDICTED: similar to Lin-7b [Pan troglodytes]	166.0	[0..3]	[207..120]
gi\|50882515, gi\|... - gi\|52219174\|ref\|NP_001004672.1\| lin7c protein [Danio rerio], gi\|51859336\|gb\|AAH81422.1\| Lin-7 homolo...	163.0	[0..1]	[198..1]
gi\|542167590\|ref... - PREDICTED: protein lin-7 homolog C [Zonotrichia albicollis] gi\|224050405 - gi\|224050405\|ref\|XP_002194172.1\| PREDICTED: lin-7 homolog C [Taeniopygia guttata] LIN7C_CHICK - Protein lin-7 homolog C OS=Gallus gallus GN=LIN7C PE=1 SV=1	161.0	[0..1]	[197..1]
gi\|157107719, gi... - gi\|157107719\|ref\|XP_001649907.1\| hypothetical protein AaeL_AAEL004846 [Aedes aegypti], gi\|157107717\|...	161.0	[0..1]	[196..1]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALVEPLGL ERDVSRAVEL LERLQRSGEL PPQKLQALQR VLQSRFCSAI REVYEQLYDT  60
   61 LDITGSAEVR AHATAKA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.44
Match:	1y74A
Description:	Solution Structure of mLin-2/mLin-7 L27 Domain Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
epidermal growth factor receptor binding	2.83728577240611	bayes_pls_golite062009
binding	1.72922707266313	bayes_pls_golite062009
protein binding	1.08813585723961	bayes_pls_golite062009
PDZ domain binding	0.950044269901752	bayes_pls_golite062009
receptor binding	0.684990774885903	bayes_pls_golite062009
protein domain specific binding	0.450006870427269	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [78-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVAAFTASEG HAHPRVVELP KTDEGLGFNI MGGKEQNSPI YISRVIPGGV ADRHGGLKRG  60
   61 DQLLSVNGVS VEGEHHEKAV ELLKAAQGSV KLVVRYTPRV LEEMEARFEK MRSARRRQQH 120
  121 HSYTSLESRG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.0
Match:	2dkrA
Description:	No description for 2dkrA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: