YRC Public Data Repository - Protein Structure Prediction

Protein:	NUD14_MOUSE
Organism:	Mus musculus
Length:	222 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUD14_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|26378444 - gi\|26378444\|dbj\|BAB28691.2\| unnamed protein product [Mus musculus]	165.0	[0..1]	[222..1]
gi\|109479992, gi... - gi\|27717381\|ref\|XP_216799.1\| PREDICTED: similar to nudix (nucleoside diphosphate linked moiety X)-ty...	158.0	[0..1]	[222..1]
NUDT14 - nudix (nucleoside diphosphate linked moiety X)-type motif 14	152.0	[0..1]	[222..1]
gi\|114655100 - gi\|114655100\|ref\|XP_001141720.1\| PREDICTED: nudix -type motif 14 [Pan troglodytes]	152.0	[0..1]	[222..1]
NUD14_BOVIN - Uridine diphosphate glucose pyrophosphatase OS=Bos taurus GN=NUDT14 PE=2 SV=1	152.0	[0..1]	[222..1]
gi\|29373950 - gi\|29373950\|emb\|CAD62374.1\| UDP-sugar diphosphatase [Sus scrofa]	151.0	[0..1]	[222..1]
gi\|167040190, gi... - gi\|167040190\|ref\|YP_001663175.1\| NUDIX hydrolase [Thermoanaerobacter sp. X514], gi\|166854430\|gb\|ABY9... gi\|241902783, gi... - gi\|241902783\|ref\|ZP_04787514.1\| NUDIX hydrolase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi... gi\|242258345, gi... - gi\|242258345\|ref\|ZP_04803159.1\| NUDIX hydrolase [Thermoanaerobacter sp. X513], gi\|242230130\|gb\|EES32... gi\|76796749, gi\|... - gi\|76796749\|ref\|ZP_00779103.1\| NUDIX hydrolase [Thermoanaerobacter ethanolicus ATCC 33223], gi\|76587...	135.0	[0..2]	[214..3]
gi\|109085043 - gi\|109085043\|ref\|XP_001086418.1\| PREDICTED: similar to nudix -type motif 14 [Macaca mulatta]	134.0	[0..24]	[222..96]
gi\|88944793, gi\|... - gi\|88944793\|ref\|ZP_01148017.1\| NTP pyrophosphohydrolases including oxidative damage repair enzymes [...	133.0	[0..5]	[208..7]

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Predicted Domain #1

Region A:
Residues: [1-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERIDGVAVG LCAHSPYLRP FTLHYRQDGV QKSWDFMKTH DSVTILMFNS SRRSLVLVKQ  60
   61 FRPAVYAGEV ERHFPGSLTA VNQDQPQELQ QALPGSAGVM VELCAGIVDQ PGLSLEEAAC 120
  121 KEAWEECGYR LVPTDLRRVA TYMSGVGLTS SRQTMFYAEV TDAQRGGPGG GLAEEGELIE 180
  181 VIHLNLDDAQ AFADNPDIPK TLGVIYAISW FFSQVVPHLS LQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.30103
Match:	1g0sA
Description:	ADP-ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.724329914463007	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: