YRC Public Data Repository - Protein Structure Prediction

Protein:	MED4_MOUSE
Organism:	Mus musculus
Length:	270 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED4_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|74216864 - gi\|74216864\|dbj\|BAE26554.1\| unnamed protein product [Mus musculus]	366.0	[0..1]	[258..10]
MED4_RAT - Mediator of RNA polymerase II transcription subunit 4 OS=Rattus norvegicus GN=Med4 PE=2 SV=1	364.0	[0..1]	[258..1]
gi\|109120699 - gi\|109120699\|ref\|XP_001100111.1\| PREDICTED: similar to Mediator complex subunit 4 (Mediator of RNA p...	357.0	[0..1]	[258..1]
gi\|114649587 - gi\|114649587\|ref\|XP_509775.2\| PREDICTED: similar to VDRIP isoform 3 [Pan troglodytes] MED4 - mediator complex subunit 4	341.0	[0..1]	[258..1]
MED4_BOVIN - Mediator of RNA polymerase II transcription subunit 4 OS=Bos taurus GN=MED4 PE=2 SV=1	341.0	[0..1]	[258..1]

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Predicted Domain #1

Region A:
Residues: [1-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASSSGEKE KERMGGVSGM AGLGSTRERL LSALEDLEVL SRELIEMLAI SRNQKLLQLE  60
   61 EENQVLELLI HRDGDFQELM KLALNQGKVH HEMQALEKEV EKRDSDIQQL QKQLKEAEQI 120
  121 LATAVYQAKE KLKSIEKARK GAISSEEIIK YAHRISASNA VCAPLTWVPG DPRRPYPTDL 180
  181 EMRSGLLGQM NNPSTSGVNG HLPGDALAAG RLPDVLAPQY PWQSNDMSVN MLPPNHSSDF 240
  241 LLEPPGHNKE NEDDVEVMST DSSSSSSDSD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.57
Match:	1jchA
Description:	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits