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View Structure Prediction Details

Protein: CSN7A_MOUSE
Organism: Mus musculus
Length: 275 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSN7A_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109095300, gi... - gi|109095304|ref|XP_001108690.1| PREDICTED: COP9 constitutive photomorphogenic homolog subunit 7A (A...
290.0 [0..1] [275..1]
gi|6120135 - gi|6120135|gb|AAF04307.1|AF193844_1 COP9 complex subunit 7a [Homo sapiens]
288.0 [0..1] [275..1]
gi|73997739 - gi|73997739|ref|XP_543849.2| PREDICTED: similar to COP9 signalosome complex subunit 7a (Signalosome ...
287.0 [0..1] [275..1]
gi|76616462, gi|... - gi|76616462|ref|XP_581310.2| PREDICTED: similar to COP9 signalosome complex subunit 7a (Signalosome ...
287.0 [0..1] [275..1]
gi|50752333 - gi|50752333|ref|XP_422740.1| PREDICTED: similar to Cops7b protein [Gallus gallus]
281.0 [0..1] [267..244]
gi|109487451, gi... - gi|62655356|ref|XP_343615.2| PREDICTED: similar to COP9 (constitutive photomorphogenic) homolog, sub...
279.0 [0..1] [267..59]
gi|114583851 - gi|114583851|ref|XP_001145635.1| PREDICTED: hypothetical protein isoform 10 [Pan troglodytes]
276.0 [0..1] [264..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEVKVTGQ NQEQFLLLAK SAKGAALATL IHQVLEAPGV YVFGELLDMP NVRELAESDF  60
   61 ASTFRLLTVF AYGTYADYLA EARNL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.732 N/A N/A a.4.1 Homeodomain-like
View Download 0.635 N/A N/A a.4.1 Homeodomain-like
View Download 0.608 N/A N/A a.4.1 Homeodomain-like
View Download 0.596 N/A N/A a.4.1 Homeodomain-like

Predicted Domain #2
Region A:
Residues: [86-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPLTDAQKNK LRHLSVVTLA AKVKCIPYAV LLEALALRNV RQLEDLVIEA VYADVLRGSL  60
   61 DQRNQRLEVD YSIGRDIQRQ DLSAIAQTLQ EWCVGCEVVL SGIEEQVSRA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.95
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [196-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQHKEQQLGL KQQIESEVAN LKKTIKVTTA AAAAATSQDP EQHLTELREP ASGTNQRQPS  60
   61 KKASKGKGLR GSAKIWSKSN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.426 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.415 a.4.5 "Winged helix" DNA-binding domain
View Download 0.375 a.3.1 Cytochrome c
View Download 0.353 a.3.1 Cytochrome c
View Download 0.318 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.315 a.3.1 Cytochrome c
View Download 0.310 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.236 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.220 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.201 d.51.1 Eukaryotic type KH-domain (KH-domain type I)


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle