YRC Public Data Repository - Protein Structure Prediction

Protein:	PTPS_MOUSE
Organism:	Mus musculus
Length:	144 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTPS_MOUSE.

Description	E-value	Query Range	Subject Range
PTPS_POERE - 6-pyruvoyl tetrahydrobiopterin synthase OS=Poecilia reticulata GN=pts PE=2 SV=1	194.0	[0..2]	[144..5]
gi\|109108666 - gi\|109108666\|ref\|XP_001108264.1\| PREDICTED: 6-pyruvoyltetrahydropterin synthase [Macaca mulatta]	187.0	[0..1]	[144..1]
gi\|114640356 - gi\|114640356\|ref\|XP_001147929.1\| PREDICTED: 6-pyruvoyltetrahydropterin synthase [Pan troglodytes]	186.0	[0..1]	[144..1]
PTPS_PONAB - 6-pyruvoyl tetrahydrobiopterin synthase OS=Pongo abelii GN=PTS PE=2 SV=1 PTPS_PONPY - 6-pyruvoyl tetrahydrobiopterin synthase - Pongo pygmaeus (Orangutan)	186.0	[0..1]	[144..1]
gi\|117645424, gi... - gi\|123994915\|gb\|ABM85059.1\| 6-pyruvoyltetrahydropterin synthase [synthetic construct], gi\|123980116\|... PTS - 6-pyruvoyltetrahydropterin synthase	185.0	[0..1]	[144..1]
gi\|165377310, gi... - gi\|76635142\|ref\|XP_583363.2\| PREDICTED: similar to 6-pyruvoyl tetrahydrobiopterin synthase precursor...	184.0	[0..1]	[144..1]
gi\|78213852, gi\|... - gi\|78213852\|ref\|YP_382631.1\| 6-pyruvoyltetrahydropterin synthase [Synechococcus sp. CC9605], gi\|7819...	183.0	[0..8]	[144..151]
gi\|47214560 - gi\|47214560\|emb\|CAF96233.1\| unnamed protein product [Tetraodon nigroviridis]	181.0	[0..5]	[144..9]
gi\|116071454, gi... - gi\|116071454\|ref\|ZP_01468722.1\| 6-pyruvoyltetrahydropterin synthase [Synechococcus sp. BL107], gi\|11...	180.0	[0..8]	[144..89]

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Predicted Domain #1

Region A:
Residues: [1-144]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAAGDLRRR ARLSRLVSFS ASHRLHSPSL SDEENLRVFG KCNNPNGHGH NYKVVVTVHG  60
   61 EIDPVTGMVM NLTDLKEYME EAIMKPLDHK NLDLDVPYFA DAVSTTENVA VYIWESLQKL 120
  121 LPVGALYKVK VFETDNNIVV YKGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.221849
Match:	1b66A
Description:	6-pyruvoyl tetrahydropterin synthase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits