YRC Public Data Repository - Protein Structure Prediction

Protein:	TPK1_MOUSE
Organism:	Mus musculus
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPK1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|83755026, gi\|... - gi\|83755027\|pdb\|2F17\|B Chain B, Mouse Thiamin Pyrophosphokinase In A Ternary Complex With Pyrithiami...	345.0	[0..1]	[243..21]
TPK1 - thiamin pyrophosphokinase 1	341.0	[0..1]	[243..1]
gi\|114616588 - gi\|114616588\|ref\|XP_519461.2\| PREDICTED: thiamin pyrophosphokinase 1 [Pan troglodytes]	339.0	[0..1]	[243..1]
TPK1_BOVIN - Thiamin pyrophosphokinase 1 OS=Bos taurus GN=TPK1 PE=2 SV=1	317.0	[0..1]	[243..1]
gi\|109473428 - gi\|109473428\|ref\|XP_001073146.1\| PREDICTED: similar to Thiamin pyrophosphokinase 1 (Thiamine pyropho...	302.0	[0..1]	[242..1]
gi\|109068707 - gi\|109068707\|ref\|XP_001094591.1\| PREDICTED: similar to thiamin pyrophosphokinase 1 [Macaca mulatta]	285.0	[0..39]	[243..123]
TPK1_ORYSJ - Thiamine pyrophosphokinase 1 OS=Oryza sativa subsp. japonica GN=TPK1 PE=2 SV=1	280.0	[0..4]	[243..18]

Back

Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHAFTPLEP LLPTGNLKYC LVVLNQPLDA RFRHLWKKAL LRACADGGAN HLYDLTEGER  60
   61 ESFLPEFVSG DFDSIRPEVK EYYTKKGCDL ISTPDQDHTD FTKCLQVLQR KIEEKELQVD 120
  121 VIVTLGGLGG RFDQIMASVN TLFQATHITP VPIIIIQKDS LIYLLQPGKH RLHVDTGMEG 180
  181 SWCGLIPVGQ PCNQVTTTGL KWNLTNDVLG FGTLVSTSNT YDGSGLVTVE TDHPLLWTMA 240
  241 IKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.221849
Match:	1ig3A
Description:	Thiamin pyrophosphokinase, substrate-binding domain; Thiamin pyrophosphokinase, catalytic domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits