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View Structure Prediction Details

Protein: TTHY_MOUSE
Organism: Mus musculus
Length: 147 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TTHY_MOUSE.

Description E-value Query
Range		 Subject
Range
TTHY_RAT - Transthyretin OS=Rattus norvegicus GN=Ttr PE=1 SV=1
 228.0 [0..1] [147..1]
gi|12852317 - gi|12852317|dbj|BAB29362.1| unnamed protein product [Mus musculus]
 224.0 [0..1] [147..1]
TTHY_ERIEU - Transthyretin OS=Erinaceus europaeus GN=TTR PE=2 SV=1
 223.0 [0..1] [147..1]
TTHY_BOVIN - Transthyretin OS=Bos taurus GN=TTR PE=1 SV=1
 221.0 [0..1] [146..1]
TTHY_CROPO - Transthyretin OS=Crocodylus porosus GN=TTR PE=1 SV=1
 216.0 [0..1] [147..1]
TTHY_CHICK - Transthyretin OS=Gallus gallus GN=TTR PE=1 SV=1
 215.0 [0..1] [147..1]
TTHY_TILRU - Transthyretin OS=Tiliqua rugosa GN=TTR PE=1 SV=1
 212.0 [0..1] [147..1]
gi|84795344 - gi|84795344|gb|ABC65926.1| transthyretin precursor [Anas platyrhynchos]
 211.0 [0..1] [147..1]
gi|2136665 - pir||S65955 transthyretin precursor - pig
TTHY_PIG - Transthyretin OS=Sus scrofa GN=TTR PE=1 SV=1
 209.0 [0..1] [147..1]

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Predicted Domain #1
Region A:
Residues: [1-147] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLRLFLLC LAGLVFVSEA GPAGAGESKC PLMVKVLDAV RGSPAVDVAV KVFKKTSEGS  60
   61 WEPFASGKTA ESGELHGLTT DEKFVEGVYR VELDTKSYWK TLGISPFHEF ADVVFTANDS 120
  121 GHRHYTIAAL LSPYSYSTTA VVSNPQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.69897
Match: 1ie4A
Description: Transthyretin (prealbumin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
thyroid hormone transmembrane transporter activity 3.15713468570674 bayes_pls_golite062009
binding 1.51642962659605 bayes_pls_golite062009
transporter activity 0.748163335007016 bayes_pls_golite062009
transmembrane transporter activity 0.528583031524624 bayes_pls_golite062009
protein binding 0.397288184240483 bayes_pls_golite062009
catalytic activity 0.24846317916908 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle