YRC Public Data Repository - Protein Structure Prediction

Protein:	RM17_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RM17_SCHPO.

Description	E-value	Query Range	Subject Range
MRPL46 - mitochondrial ribosomal protein L46	285.0	[0..11]	[266..20]
gi\|114658725 - gi\|114658725\|ref\|XP_510572.2\| PREDICTED: mitochondrial ribosomal protein L46 isoform 2 [Pan troglody...	283.0	[0..11]	[266..20]
gi\|42554222, gi\|... - gi\|46124755\|ref\|XP_386931.1\| hypothetical protein FG06755.1 [Gibberella zeae PH-1], gi\|42554222\|gb\|E...	276.0	[0..12]	[267..39]
RM46_RAT - 39S ribosomal protein L46, mitochondrial OS=Rattus norvegicus GN=Mrpl46 PE=2 SV=1	274.0	[0..12]	[266..17]
gi\|85090829 - gi\|85090829\|ref\|XP_958605.1\| hypothetical protein NCU07560 [Neurospora crassa OR74A] gi\|28919980, gi\|... - gi\|32414733\|ref\|XP_327846.1\| hypothetical protein [Neurospora crassa], gi\|28919980\|gb\|EAA29369.1\| co...	273.0	[0..28]	[267..75]
gi\|145010567, gi... - gi\|39940140\|ref\|XP_359607.1\| hypothetical protein MGG_05170 [Magnaporthe grisea 70-15], gb\|EAA52478....	272.0	[0..9]	[267..33]
gi\|109082282 - gi\|109082282\|ref\|XP_001088970.1\| PREDICTED: similar to mitochondrial ribosomal protein L46 isoform 2...	270.0	[0..10]	[266..19]
gi\|49106384, gi\|... - gi\|67900594\|ref\|XP_680553.1\| hypothetical protein AN7284.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	264.0	[0..10]	[267..377]
RM46_PONPY - 39S ribosomal protein L46, mitochondrial precursor - Pongo pygmaeus (Orangutan) RM46_PONAB - 39S ribosomal protein L46, mitochondrial OS=Pongo abelii GN=MRPL46 PE=2 SV=1	262.0	[0..11]	[266..20]
gi\|44985293 - gi\|44985293\|gb\|AAS54006.1\| AFR635Cp [Ashbya gossypii ATCC 10895] gi\|45199153, gi\|... - gi\|45199153\|ref\|NP_986182.1\| AFR635Cp [Ashbya gossypii ATCC 10895], gi\|44985293\|gb\|AAS54006.1\| AFR63...	259.0	[0..21]	[266..5]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLKRNIINM QRSFSRQFHI SVRNSIQSSK PLSNSTPLKG CSVGTILIRS PILTRQPSEF  60
   61 EKSIYKYNAE LWNELSDPLP AEFYFKKGSV GEKDWQERQK TLKGKESPFE TIFGKERKEM 120
  121 ESNKLLD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.279	0.890	structural constituent of ribosome	c.55.4	Translational machinery components

Predicted Domain #2

Region A:
Residues: [128-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SATHLQSRVT EADTKNDERS TLRSLDKSLY LLVKKSKSSG WQFPNTPVTS SEKALHLLCQ  60
   61 DLLKNILDEN SLTWLVARHP LALLKTEQEK TFLLRARLLN GLDVPNLQNV YDWVWCTYDE 120
  121 LKNKLSPSSW DSVKNILSDR L

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.42
Match:	1kt9A
Description:	Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.38338559299412	bayes_pls_golite062009
binding	0.881558273069274	bayes_pls_golite062009
nucleic acid binding	0.495924061190848	bayes_pls_golite062009
RNA binding	0.44030858339937	bayes_pls_golite062009
protein binding	0.358912650308843	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: