YRC Public Data Repository - Protein Structure Prediction

Protein:	IMT2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	345 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IMT2_SCHPO.

Description	E-value	Query Range	Subject Range
CSH1 - Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex... gi\|151946550 - gi\|151946550\|gb\|EDN64772.1\| CSG1/SUR1-like protein [Saccharomyces cerevisiae YJM789] gi\|207347608 - gi\|207347608\|gb\|EDZ73722.1\| YBR161Wp-like protein [Saccharomyces cerevisiae AWRI1631] CSH1_YEAST - Mannosyl phosphorylinositol ceramide synthase CSH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /... gi\|190408686 - gi\|190408686\|gb\|EDV11951.1\| mannosyl phosphorylinositol ceramide synthase SUR1 [Saccharomyces cerevi...	279.0	[0..8]	[317..5]
gi\|159122397 - gi\|159122397\|gb\|EDP47518.1\| MIPC synthase subunit (SurA), putative [Aspergillus fumigatus A1163] gi\|66845237, gi\|... - gi\|70984184\|ref\|XP_747610.1\| MIPC synthase subunit (SurA) [Aspergillus fumigatus Af293], gi\|66845237...	261.0	[0..8]	[327..5]
gi\|169776999 - gi\|169776999\|ref\|XP_001822965.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83771702 - gi\|83771702\|dbj\|BAE61832.1\| unnamed protein product [Aspergillus oryzae]	257.0	[0..8]	[327..5]
gi\|31323648 - gi\|31323648\|gb\|AAP47108.1\| MIPC synthase; SURA [Aspergillus nidulans] gi\|67540728, gi\|... - gi\|67540728\|ref\|XP_664138.1\| hypothetical protein AN6534.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	253.0	[0..69]	[306..46]
gi\|90307821, gi\|... - gi\|90307821\|gb\|EAS37452.1\| hypothetical protein CIMG_02806 [Coccidioides immitis RS], gi\|119196863\|r...	251.0	[0..10]	[327..7]
gi\|49528904, gi\|... - gi\|50294358\|ref\|XP_449590.1\| hypothetical protein CAGL0M05621g [Candida glabrata CBS138], gi\|4952890... gi\|49528904 - gi\|49528904\|emb\|CAG62566.1\| unnamed protein product [Candida glabrata]	250.0	[0..8]	[317..5]
gi\|46435801, gi\|... - gi\|68483863\|ref\|XP_714110.1\| hypothetical protein CaO19.11558 [Candida albicans SC5314], gi\|68483590... orf19.4077, orf1... - MIT1 CGDID:CAL0004910 Assembly 19, Contig19-10196 (27331, 28965) CDS, translated using codon table 1...	248.0	[0..31]	[322..5]
gi\|111062246, gi... - gi\|169612115\|ref\|XP_001799475.1\| hypothetical protein SNOG_09174 [Phaeosphaeria nodorum SN15], gi\|11...	239.0	[0..10]	[315..7]

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Predicted Domain #1

Region A:
Residues: [1-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKVIYKFAV FAAVNFFLMS SIVLYFNNEF LMFADRCTKD IIPSEELRYL RQVLNDSIPS  60
   61 KDEPLPTLKL DSLNDISGEP VIPKIIHQTW KTTEVPEGWK GAQQSCIDLH PDYEYILWTD 120
  121 EMSRNFIADN YPWFLPYFDA YPFNVQRADV IRYFVLYHYG GNYIDLDDGC RQRLDSLLYY 180
  181 PVWVRRTDPV GVSNDVMGSV PHHPYFELII QNLEKNAKSY WLPYLTIMLS TGPLSISFLW 240
  241 EKYKRQLPNP PAFYDHIRVL LERDYKFSND SYFTFYEGSS WHNNDAGIIL WANRHLAYVI 300
  301 VAGFCLYFIL SYMFFSKLLD SRYVQRFVTS KRKQPTLPLA LQEDV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.34
Match:	2bvlA
Description:	Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	2.7655825717134	bayes_pls_golite062009
galactosyltransferase activity	2.66132518558087	bayes_pls_golite062009
UDP-galactosyltransferase activity	2.41947487589824	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.12459108032305	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.87269663092513	bayes_pls_golite062009
catalytic activity	1.73979371332125	bayes_pls_golite062009
nucleotidyltransferase activity	1.47767908405723	bayes_pls_golite062009
transferase activity	1.18156663897445	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.18110459041383	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	1.10264155774645	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.997346543848255	bayes_pls_golite062009
alpha-1,3-galactosyltransferase activity	0.591293545650568	bayes_pls_golite062009
cytidylyltransferase activity	0.507775977022676	bayes_pls_golite062009
mannosyltransferase activity	0.435965261897494	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.141504339903925	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: