YRC Public Data Repository - Protein Structure Prediction

Protein:	CARME_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	373 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CARME_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|109111848 - gi\|109111848\|ref\|XP_001094584.1\| PREDICTED: similar to CG11596-PA, isoform A [Macaca mulatta]	527.0	[0..10]	[365..256]
gi\|94386253, gi\|... - gi\|94387428\|ref\|XP_991095.1\| PREDICTED: similar to CG11596-PA, isoform A [Mus musculus], gi\|94386253...	525.0	[0..2]	[365..84]
CARME_RAT - Carnosine N-methyltransferase OS=Rattus norvegicus GN=Carnmt1 PE=1 SV=1	520.0	[0..2]	[365..48]
gi\|114625050 - gi\|114625050\|ref\|XP_528328.2\| PREDICTED: similar to Chromosome 9 open reading frame 41 [Pan troglody...	518.0	[0..10]	[365..131]
gi\|73946783 - gi\|73946783\|ref\|XP_533523.2\| PREDICTED: similar to CG11596-PA, isoform A [Canis familiaris]	511.0	[0..10]	[365..67]
C9orf41 - chromosome 9 open reading frame 41 gi\|190690459, gi... - gi\|190691835\|gb\|ACE87692.1\| chromosome 9 open reading frame 41 protein [synthetic construct], gi\|190... ENSPTRT00000038890 - null	511.0	[0..10]	[365..65]

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Predicted Domain #1

Region A:
Residues: [1-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYDEEEVKV LKEVLSAFFL YRQYAHTITQ QKRKSMSRLS FEHKDLLLQD SDNNFLKHLS  60
   61 RIDQCIEQNS VLAEAIANAA IPVFCSDFDQ NELFHVNVDM MQKVSSTLKQ IARDWSTECV 120
  121 EERRTTYAPF IEELNSLFPS DSIDRSKIRV LVPGSGLGRL AFDIAVEGFA CQGNEFSYFM 180
  181 LLTSHFILNC VKQENQFLVY PYIHSFSNHV MRDDQVRSLN IPDAVPSQYL RNSQNFSMAA 240
  241 GDFLEVYGTE ESRDSFQVVA TCFFIDTTKN ILDYLDTIKN CLVDGGYWIN LGPLLYHFES 300
  301 EGTSNSNSDS QQQPFVELTL EQLFYVMDSM GFEVLKHNSV DTTYMGDKRS MLEWIYHPHY 360
  361 WVCRLQKSKL RFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.05
Match:	1tw2A
Description:	Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	1.0221592961184	bayes_pls_golite062009
catalytic activity	0.403277401956396	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: