YRC Public Data Repository - Protein Structure Prediction

Protein:	RPC3_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	591 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPC3_SCHPO.

Description	E-value	Query Range	Subject Range
RPC3_BOVIN - DNA-directed RNA polymerase III subunit RPC3 OS=Bos taurus GN=POLR3C PE=2 SV=1	583.0	[0..1]	[587..1]
gi\|73981410 - gi\|73981410\|ref\|XP_540277.2\| PREDICTED: similar to polymerase (RNA) III (DNA directed) polypeptide C...	581.0	[0..1]	[587..1]
RPC3_MOUSE - DNA-directed RNA polymerase III subunit RPC3 OS=Mus musculus GN=Polr3c PE=1 SV=1	576.0	[0..1]	[587..1]
gi\|208967092 - gi\|208967092\|dbj\|BAG73560.1\| polymerase (RNA) III (DNA directed) polypeptide C [synthetic construct] POLR3C - polymerase (RNA) III (DNA directed) polypeptide C (62kD) gi\|114558427, gi... - gi\|114558427\|ref\|XP_513732.2\| PREDICTED: polymerase (RNA) III (DNA directed) polypeptide C (62kD) is...	576.0	[0..1]	[587..1]
RPC3_RAT - DNA-directed RNA polymerase III subunit RPC3 OS=Rattus norvegicus GN=Polr3c PE=2 SV=1	571.0	[0..1]	[587..1]
gi\|114558429 - gi\|114558429\|ref\|XP_001161518.1\| PREDICTED: polymerase (RNA) III (DNA directed) polypeptide C (62kD)...	564.0	[0..1]	[579..1]
RPC3_DANRE - DNA-directed RNA polymerase III subunit RPC3 OS=Danio rerio GN=polr3c PE=2 SV=1	549.0	[0..1]	[587..1]
gi\|42545532, gi\|... - gi\|46107524\|ref\|XP_380821.1\| hypothetical protein FG00645.1 [Gibberella zeae PH-1], gi\|42545532\|gb\|E...	544.0	[0..1]	[589..3]

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Predicted Domain #1

Region A:
Residues: [1-130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQYAVELCE ILVEEFFGDC CSAVASALLR HGRLTIPMLQ KRTSLPGPKI RQALVSLMQH  60
   61 HMVLYVTVIE NVREVTYYET QWKEIYNILR KGKDVYLISQ KLNQEAASVV KYLSTQGRAR 120
  121 VLEVFNAFDK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.16
Match:	1sfxA
Description:	X-ray crystal structure of putative HTH transcription regulator from Archaeoglobus fulgidus
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [131-408]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVDGSDEESR MMQKNLTELI YQKFLLVVQP RHLIPVGDQE MQLRIKHLDR RKSENVSEIK  60
   61 KNREVDDSVA LEMLELRAAD MSELQGLTRK PKESIPHPTK RRKRAVGSAP SVSTDLNNIL 120
  121 DDDNSILVPD LSAHVRINSG KLSVLSKNAR LTHWVERRIG KSTSLVYSHV LSMLEPRLFS 180
  181 ISNQSPVFTL TTMELTRNFP NDIDVESSIV DKQYSVNSAS NELRVMEKLN ELDELAEEDN 240
  241 YEESVDENAN RKSKVLAQHL ELLADCSLKF ISKIGNRG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [409-591]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEWAVNFTH LTDMLRAIEY ENFIEQKFGE RAIRLLRIIK DKGKIEEKQL ANIALLRQRD  60
   61 LRTVLQAMAE IGALELQEVP RSSDRAPSKT FFLWFHRPDR AYSLLLDELY HVIARLYMRL 120
  121 RDARAQRAQL IEKAERIDIK GNEEQYLQKF EQAELKKLYS YEEKLLLQAS RLDDMVLVFR 180
  181 DNL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.63
Match:	1q1hA
Description:	An extended winged helix domain in general transcription factor E/IIE alpha
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits