YRC Public Data Repository - Protein Structure Prediction

Protein:	GLO21_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	256 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLO21_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|83772861 - gi\|83772861\|dbj\|BAE62989.1\| unnamed protein product [Aspergillus oryzae] gi\|169779315 - gi\|169779315\|ref\|XP_001824122.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|220692964, gi... - gi\|238499953\|ref\|XP_002381211.1\| hydroxyacylglutathione hydrolase, putative [Aspergillus flavus NRRL...	220.0	[0..3]	[255..1]
gi\|115387325, gi... - gi\|115387325\|ref\|XP_001211168.1\| hypothetical protein ATEG_01990 [Aspergillus terreus NIH2624], gi\|1...	220.0	[0..13]	[255..465]
gi\|39946066, gi\|... - gi\|39946066\|ref\|XP_362570.1\| hypothetical protein MG08153.4 [Magnaporthe grisea 70-15], gb\|EAA57184....	219.0	[0..13]	[254..507]
GLO22_SCHPO - Probable hydroxyacylglutathione hydrolase C13B11.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC... SPCC13B11.03c - hydroxyacylglutathione hydrolase	214.0	[0..1]	[254..1]
gi\|28922635, gi\|... - gi\|32404876\|ref\|XP_323051.1\| hypothetical protein ( (AL513443) probable hydroxyacylglutathione hydro... gi\|85101167 - gi\|85101167\|ref\|XP_961096.1\| hypothetical protein ( (AL513443) probable hydroxyacylglutathione hydro...	205.0	[0..3]	[254..1]
gi\|66911967 - gi\|66911967\|gb\|AAH97301.1\| Hagh protein [Rattus norvegicus]	203.0	[0..1]	[254..45]
HAGH - hydroxyacylglutathione hydrolase	201.0	[0..1]	[254..49]
gi\|66851005, gi\|... - gi\|70997233\|ref\|XP_753369.1\| hydroxyacylglutathione hydrolase [Aspergillus fumigatus Af293], gi\|6685...	201.0	[0..3]	[255..1]
gi\|115891513, gi... - gi\|115949376\|ref\|XP_001191822.1\| PREDICTED: similar to hydroxyacyl glutathione hydrolase [Strongyloc...	200.0	[0..1]	[254..1]

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Predicted Domain #1

Region A:
Residues: [1-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFHITPIWM WKGTGNNYAY LLTCDKTKIT AIVDPAEPES VIPVIKEKTA KKEIDLQYIL  60
   61 TTHHHYDHAG GNEDILSYFP SLKVYGGKNA SGVTYTPKDK EIFKVGEVQV EALHTPCHTQ 120
  121 DSICYYVSSP SKRAVFTGDT LFTSGCGRFF EGDAKQMDYA LNHVLAALPD DTVTYPGHEY 180
  181 TKSNAKFSST IFSTPELTKL VDFCKNHEST TGHFTIGDEK KFNPFMCLGL ESVQKAVGSS 240
  241 DPITVMKKLR DMKNAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.39794
Match:	1qh3A
Description:	Glyoxalase II (hydroxyacylglutathione hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydroxyacylglutathione hydrolase activity	3.53012507604564	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009
binding	0.900972948435178	bayes_pls_golite062009
thiolester hydrolase activity	0.802604883362264	bayes_pls_golite062009
hydrolase activity	0.021392930321391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: