YRC Public Data Repository - Protein Structure Prediction

Protein:	YIE2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	430 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIE2_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|40740239, gi\|... - gi\|67527829\|ref\|XP_661772.1\| hypothetical protein AN4168.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	325.0	[0..1]	[424..3]
gi\|83767232 - gi\|83767232\|dbj\|BAE57371.1\| unnamed protein product [Aspergillus oryzae] gi\|169769807 - gi\|169769807\|ref\|XP_001819373.1\| hypothetical protein [Aspergillus oryzae RIB40]	323.0	[0..1]	[428..3]
gi\|114191932, gi... - gi\|115398920\|ref\|XP_001215049.1\| hypothetical protein ATEG_05871 [Aspergillus terreus NIH2624], gi\|1...	321.0	[0..1]	[428..3]
gi\|70991661, gi\|... - gi\|70991661\|ref\|XP_750679.1\| DUF500 and SH3 domain protein [Aspergillus fumigatus Af293], gi\|6684831...	317.0	[0..1]	[423..3]
gi\|46135963, gi\|... - gi\|46135963\|ref\|XP_389673.1\| hypothetical protein FG09497.1 [Gibberella zeae PH-1], gi\|42553443\|gb\|E...	316.0	[0..1]	[429..1]
gi\|119193753, gi... - gi\|90306266\|gb\|EAS35897.1\| hypothetical protein CIMG_01251 [Coccidioides immitis RS], gi\|119193753\|r...	306.0	[0..1]	[429..3]
gi\|44983569 - gi\|44983569\|gb\|AAS52668.1\| AEL017Wp [Ashbya gossypii ATCC 10895] gi\|44983569, gi\|... - gi\|45190590\|ref\|NP_984844.1\| AEL017Wp [Ashbya gossypii ATCC 10895], gi\|44983569\|gb\|AAS52668.1\| AEL01...	298.0	[0..1]	[429..1]
YSC84 - Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patc... YSC84_YEAST - Protein YSC84 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YSC84 PE=1 SV=2 gi\|190405801 - gi\|190405801\|gb\|EDV09068.1\| hypothetical protein SCRG_04722 [Saccharomyces cerevisiae RM11-1a]	297.0	[0..1]	[430..1]
gi\|85085600 - gi\|85085600\|ref\|XP_957527.1\| hypothetical protein NCU03888 [Neurospora crassa OR74A] gi\|32405188, gi\|... - gi\|32405188\|ref\|XP_323207.1\| hypothetical protein [Neurospora crassa], gi\|28918620\|gb\|EAA28291.1\| hy...	295.0	[0..1]	[429..1]
gi\|49653999, gi\|... - gi\|50428139\|ref\|XP_458333.1\| hypothetical protein DEHA0C16093g [Debaryomyces hansenii CBS767], gi\|49...	294.0	[0..17]	[429..5]

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Predicted Domain #1

Region A:
Residues: [1-80]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLHNPLPSS LKSECKKAGK ILTSFVDPRQ TLGAQEVIPP SVLTNAKGLV IMTVLKAGFL  60
   61 FSGRIGSGLI VARLDDGTWS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.473	0.351	actin cortical patch	a.39.1	EF-hand
View	Download	0.412	0.231	actin cortical patch	a.4.1	Homeodomain-like
View	Download	0.342	0.013	actin cortical patch	a.29.2	Bromodomain
View	Download	0.339	0.008	actin cortical patch	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.388	N/A	N/A	a.4.1	Homeodomain-like

Predicted Domain #2

Region A:
Residues: [81-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APSAVMTGGM GVGAQIGSEL TDFVIILNSK AAVQTFARLG SITLGGNLSI AAGPLGRNAE  60
   61 AGGGASVGGM APMFSYSKTK GLFAGVSLEG SVLVERRDAN RSLYRGDITA KRLLSGQVAQ 120
  121 PAAADPLYRV LNSKIFNL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	87.221849
Match:	PF04366.3
Description:	No description for PF04366.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.423	0.829	actin filament organization	c.37.1	P-loop containing nucleoside triphosphate hydrolases
View	Download	0.253	0.103	actin cortical patch	c.2.1	NAD(P)-binding Rossmann-fold domains
View	Download	0.259	0.007	actin cortical patch	c.62.1	vWA-like
View	Download	0.222	0.004	actin cortical patch	c.51.1	Anticodon-binding domain of Class II aaRS

Predicted Domain #3

Region A:
Residues: [219-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRGDEGDIYN DVPIYADDEP EDIWGPSSKS TKRRDSADRS SSYSRRGDSY RSNRSRAHDD  60
   61 DDEDDYSFSR SKSLSRKTAG GSLRSSKMDN RRSKYADTPS PRRSRSYSDE DEESVYSSDV 120
  121 STESSSQFSS RS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [351-430]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEYSKPSRPT APKPKFKQDS LGPNQARAMY SFAGEQPGDL SFQKGDIIDI VERSGSHDDW  60
   61 WTGRIGYREG IFPANYVKLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.39794
Match:	2a08A
Description:	No description for 2a08A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits