YRC Public Data Repository - Protein Structure Prediction

Protein:	PLD1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	1369 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLD1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|56566298 - gi\|56566298\|gb\|AAN75713.2\| SPO14 [Cryptococcus neoformans var. neoformans]	1074.0	[0..35]	[1369..2]
gi\|56566258 - gi\|56566258\|gb\|AAN75170.2\| SPO14 [Cryptococcus neoformans var. grubii]	1073.0	[0..35]	[1369..2]
gi\|49092238, gi\|... - gi\|67525971\|ref\|XP_661047.1\| hypothetical protein AN3443.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	1049.0	[0..62]	[1333..702]
gi\|134088307, gi... - gi\|50258665\|gb\|EAL21350.1\| hypothetical protein CNBD0470 [Cryptococcus neoformans var. neoformans B-... gi\|58266764, gi\|... - gi\|58266764\|ref\|XP_570538.1\| hypothetical protein [Cryptococcus neoformans var. neoformans JEC21], g...	1044.0	[0..35]	[1341..2]
gi\|85085885 - gi\|85085885\|ref\|XP_957594.1\| hypothetical protein [Neurospora crassa OR74A] gi\|40882328, gi\|... - gi\|40882328\|emb\|CAF06150.1\| related to phospholipase D [Neurospora crassa], gi\|32405322\|ref\|XP_32327...	1036.0	[0..57]	[1303..279]
gi\|54112190 - gi\|54112190\|gb\|AAV28792.1\| SPO14p [Cryptococcus gattii] gi\|54112190 - gi\|54112190\|gb\|AAV28792.1\| SPO14p [Cryptococcus gattii]	1031.0	[0..35]	[1369..2]
gi\|42547300, gi\|... - gi\|46136803\|ref\|XP_390093.1\| hypothetical protein FG09917.1 [Gibberella zeae PH-1], gi\|42547300\|gb\|E...	1028.0	[0..58]	[1314..274]
gi\|145018084, gi... - gi\|39973787\|ref\|XP_368284.1\| hypothetical protein MGG_00960 [Magnaporthe grisea 70-15], gb\|EAA49302....	1027.0	[0..63]	[1302..123]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIHQGGNSV IDNVPYSLNT NVNDSIYSEK GTGRKDAEDH TPSKITDLEK NVDHSIPSFP  60
   61 ENDPKNYSEF VNLNPPKRPD LEHTRGSSWH TASENVNDLA ANDSTRVQTP EFITQTMEDE 120
  121 NVEVPPLERD ERDAAAAHTS KANRNSARQM WAQLMASVRK FKREDEKPIL KENLP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [176-525]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AINLFEAGIP ASLPIAKHFI RDKSGQPVLP IITDLIKVSV LDVEPKHNRI HSTFTIQVEY  60
   61 GTGPHAIRWL IYRQLRDFIN LHSHFLFFEF QHRFSGRRMK LPKFPKEVLP YLVKLRGYQK 120
  121 ILYSNPSDQL IDETHSISDI SWESHSQDGD RTTGQPRHAN NGRKKHGNFW TIQGNTLGVY 180
  181 LQEMIHNLQF FPEVNVLYSF LEFSSLGLYL AGAGTFHGKE GFATLKRNYS PTQYMLCCNT 240
  241 TMMKTRSQPF WIIVSESCII LCDNMLSMQP ADVFIWDVDF EITRKNFRKA HSKDTNEKIR 300
  301 LSHHSFKIKN RQKVMKLSVR SGRWLQQFIN SVQVAQGLTA WCEIHRFDSF

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.44
Match:	1u5eA
Description:	Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.0857989342765	bayes_pls_golite062009
protein binding	1.98056222560389	bayes_pls_golite062009
transporter activity	1.29925758003665	bayes_pls_golite062009
phospholipid binding	0.864843473490307	bayes_pls_golite062009
substrate-specific transporter activity	0.552872712432362	bayes_pls_golite062009
phosphoinositide binding	0.45899353522401	bayes_pls_golite062009
protein domain specific binding	0.432003190263252	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [526-1023]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVRTNVAVQ WMVDARDHMW NVSRAIKNAK RCIMIHGWWL SPELQMRRPY SMAHKWRIDR  60
   61 ILNEKAHEGV MVYIMIYRNI DATIPIDSFH TKEHLQSLHP NIYVIRSPSH FRQNALFWAH 120
  121 HEKLVVVDDA ITFIGGIDLC FGRYDTPQHI LYDDKPVADK TGLCEQTWRG KDYSNARVHD 180
  181 FFDLTEPYKD MYDRLAVPRM GWHDVSMCII GQPARDAARH FVQRWNYLIQ CKKPARKTPL 240
  241 LIPPPDFTTD QLTDSQLTGT CEVQVLRSAG LWSLGLVDTV EQSIQNAYVT CIEKSEHFIY 300
  301 IENQFFVTST TCEGTTIENR VGDALVERII RAHKNNEKWR GVIMIPLLPG FEGQIDLQEG 360
  361 GSLRLIVECQ YRSICHGEHS IFGRLNAKGI DGSKYLRFYG LRGWAHLGEN HELVTEMIYV 420
  421 HAKILIADDR VAVIGSANIN ERSLLGNRDS EIAAVIRDTL TIDSKMDGKP YKVGKFAHTL 480
  481 RKRLMREHLG LETDVLEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.154902
Match:	1f0iA
Description:	Phospholipase D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoric diester hydrolase activity	1.55477881010087	bayes_pls_golite062009
catalytic activity	1.29236214516383	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.97354820978871	bayes_pls_golite062009
binding	0.782852985815333	bayes_pls_golite062009
protein binding	0.438178121330569	bayes_pls_golite062009
transferase activity	0.417847571627092	bayes_pls_golite062009
kinase activity	0.41582825017763	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.398900256450913	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [1024-1073]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REYNMDGLDR DTEWKRVEVW TPDEGNAING SAYTAEELKM KYRSQSQFTT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [1074-1284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPDILRKAEK SMKKLDQRVS LIPSSIEFNI KTQKDKVEFE KNYEKSKKGP DVIANALVGG  60
   61 IPLSLKTKED SLYELSKFSQ CGEDQRPMVL KDPDHLVPEP SRPHCGNGLV FYDDIPLLEV 120
  121 NPISGETIPK FDASSFEDPV CDEFFEDIWS KVASNNTTIY RHIFRCVPDD EMLTWESYNE 180
  181 WKKYGKRFKE EQARWRQEEL SNLHETHEKS E

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [1285-1369]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDPKNPKAGS QGSGNTSASE DSKTEKPKTR TNNGLQVPDK RVVYDLLRGI RGQLVELPLK  60
   61 WMSTESNARN WLSSIDKIPP LEIYD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: