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View Structure Prediction Details

Protein: PRI2_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRI2_SCHPO.

Description E-value Query
Range
Subject
Range
gi|145013718, gi... - gi|39977757|ref|XP_370266.1| hypothetical protein MGG_06763 [Magnaporthe grisea 70-15], gb|EAA55106....
585.0 [0..1] [456..1]
PRIM2 - primase, DNA, polypeptide 2 (58kDa)
gi|167774191 - gi|167774191|gb|ABZ92530.1| primase, DNA, polypeptide 2 (58kDa) [synthetic construct]
577.0 [0..13] [458..9]
PRI2_MOUSE - DNA primase large subunit OS=Mus musculus GN=Prim2 PE=1 SV=1
574.0 [0..12] [458..8]
gi|49084390, gi|... - gi|67515957|ref|XP_657864.1| hypothetical protein AN0260.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
572.0 [0..1] [456..1]
PRI2_RAT - DNA primase large subunit OS=Rattus norvegicus GN=Prim2 PE=2 SV=1
572.0 [0..11] [458..7]
gi|109071613 - gi|109071613|ref|XP_001110968.1| PREDICTED: similar to DNA primase large subunit, 58kDa [Macaca mula...
571.0 [0..13] [458..9]
gi|37681907, gi|... - gi|63101257|gb|AAH95387.1| Zgc:110727 [Danio rerio], gi|47550859|ref|NP_999947.1| DNA primase polype...
570.0 [0..13] [458..6]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRTTKSRVV EKNQNFSSAS FESLSYPTRL NFYKKPPVSE ISIEEFETWA IDRLVVLGEI  60
   61 ESAMLRNKTK NELNGIIKKI LDKRLPMSSN MARTV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.652 0.060 DNA primase activity a.118.8 TPR-like
View Download 0.684 0.040 DNA primase activity a.24.3 Cytochromes
View Download 0.538 0.025 DNA primase activity f.14.1 Voltage-gated potassium channels
View Download 0.650 0.004 DNA primase activity a.118.11 Cytochrome c oxidase subunit E
View Download 0.751 N/A N/A a.112.1 Description not found.

Predicted Domain #2
Region A:
Residues: [96-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGNSLDEERR KDHYSHFILR LAFSRSDELR IRFLRAESTL FRFRFVNEET RERQAFIDSL  60
   61 DFQWESVSQE EKDVFYEKLQ ASSQRNIENE SFFKVPFFKV PDLVERRAVF VHKGYAYVPF 120
  121 SEQVSLVVEE FEENLKKALE STAKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1zt2B
Description: Heterodimeric structure of the core primase.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [241-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPRLDEDDRL LPILNHLSKG FVAPESSIVA PKSGAITAGQ VDSFVSHFPL CAKHLHEVLK  60
   61 RDKHLRHFGR LQYGLFLKDI GLSVDEALVF WRKSFTNVTE DKFNKEYRYN IRHTYGLEGN 120
  121 RKNYKGYNCQ QILTGPQLGP GDAHGCPYRT YSVNNLVSAL ASMGIAPDSA GCREVVEAVK 180
  181 ARHYHIACTR VFELTHPNVG SLEESIHHPL QYFQLSLES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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