YRC Public Data Repository - Protein Structure Prediction

Protein:	SULH2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	840 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SULH2_SCHPO.

Description	E-value	Query Range	Subject Range
SULH1_SCHPO - Probable sulfate permease C3H7.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC3H7.... SPBC3H7.02 - sulfate transporter	533.0	[0..70]	[814..83]
CYS14_NEUCR, CY1... - Sulfate permease 2 OS=Neurospora crassa GN=cys-14 PE=2 SV=3, (P23622) Sulfate permease II CYS14_NEUCR - Sulfate permease 2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FG...	514.0	[0..56]	[808..2]
gi\|82659470 - gi\|82659470\|gb\|ABB88849.1\| sulfate permease [Emericella nidulans] gi\|67524545, gi\|... - gi\|67524545\|ref\|XP_660334.1\| hypothetical protein AN2730.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	494.0	[0..57]	[808..31]
gi\|211585935 - gi\|211585935\|emb\|CAP93672.1\| sulfate permease SutB-Penicillium chrysogenum [Penicillium chrysogenum ... gi\|6502992 - gi\|6502992\|gb\|AAF14539.1\|AF163974_1 sulfate permease SutB [Penicillium chrysogenum]	493.0	[0..67]	[808..45]
gi\|169770933 - gi\|169770933\|ref\|XP_001819936.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83767795 - gi\|83767795\|dbj\|BAE57934.1\| unnamed protein product [Aspergillus oryzae]	479.0	[0..71]	[808..46]
gi\|38103696, gi\|... - gi\|39944230\|ref\|XP_361652.1\| hypothetical protein MG04126.4 [Magnaporthe grisea 70-15], gb\|EAA50367....	476.0	[0..77]	[808..129]
gi\|115388485, gi... - gi\|115388485\|ref\|XP_001211748.1\| hypothetical protein ATEG_02570 [Aspergillus terreus NIH2624], gi\|1...	474.0	[0..71]	[808..46]
gi\|32406346, gi\|... - gi\|32406346\|ref\|XP_323786.1\| hypothetical protein [Neurospora crassa], gi\|28918602\|gb\|EAA28274.1\| hy... gi\|85085443 - gi\|85085443\|ref\|XP_957510.1\| hypothetical protein [Neurospora crassa OR74A]	470.0	[0..47]	[808..59]
gi\|42546369, gi\|... - gi\|46108368\|ref\|XP_381242.1\| hypothetical protein FG01066.1 [Gibberella zeae PH-1], gi\|42546369\|gb\|E...	464.0	[0..69]	[808..37]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAWGWVRNK FSSEDDYNDG ASNKDYPDRF NEFDNSQNDH NDYTQNNAQF QNAQTTTFGR  60
   61 TISRVKAYYE IPEDDELDEL ASIPQWFKKN VTSNIFKNFL HYLKSLFPII EWLPNY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [117-551]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPYWLINDLI AGITVGCVVV PQGMSYAKVA TLPSEYGLYS SFVGVAIYCF FATSKDVSIG  60
   61 PVAVMSLITA KVIANVMAKD ETYTAPQIAT CLALLAGAIT CGIGLLRLGF IIEFIPVPAV 120
  121 AGFTTGSALN ILSGQVPALM GYKNKVTAKA TYMVIIQSLK HLPDTTVDAA FGLVSLFILF 180
  181 FTKYMCQYLG KRYPRWQQAF FLTNTLRSAV VVIVGTAISY AICKHHRSDP PISIIKTVPR 240
  241 GFQHVGVPLI TKKLCRDLAS ELPVSVIVLL LEHISIAKSF GRVNDYRIVP DQELIAMGVT 300
  301 NLIGIFFNAY PATGSFSRSA IKAKAGVKTP IAGIFTAAVV ILSLYCLTDA FYYIPNAILS 360
  361 AVIIHAVTDL ILPMKQTILF WRLQPLEACI FFISVIVSVF SSIENGIYVS VCLAAALLLL 420
  421 RIAKPHGSFL GKIQA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.988
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [552-743]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANKYGSDNIA NVRDIYVPLE MKEENPNLEI QSPPPGVFIF RLQESFTYPN ASRVSTMISR  60
   61 RIKDLTRRGI DNIYVKDIDR PWNVPRQRKK KENSEIEDLR PLLQAIIFDF SAVNNLDTTA 120
  121 VQSLIDIRKE LEIYANETVE FHFTNIRSGW IKRTLVAAGF GKPKGHAVDA SVCVEVAAPL 180
  181 RDANLSAESS RN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.51
Match:	1auzA
Description:	SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS, NMR, 24 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.14643407404573	bayes_pls_golite062009
protein binding	1.48694301635456	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [744-840]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSRIITPIYD DEEGNVSGHI YELDGKNNSD LSMHCQKGSN QVEIEFVEFN SRKYPFFHVD  60
   61 VASAVVDLQH RLLSPQKSDS FGSLKEGGTT TIKKIEN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.607	0.823	secondary active sulfate transmembrane transporter activity	b.1.1	Immunoglobulin

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: