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View Structure Prediction Details

Protein: PCTL_MOUSE
Organism: Mus musculus
Length: 291 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCTL_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109107850 - gi|109107850|ref|XP_001115167.1| PREDICTED: similar to START domain containing 10 isoform 8 [Macaca ...
300.0 [0..1] [291..69]
gi|149068740, gi... - gi|61556854|ref|NP_001013087.1| StAR-related lipid transfer (START) domain containing 10 [Rattus nor...
299.0 [0..1] [291..1]
gi|4929573, gi|1... - gi|4929573|gb|AAD34047.1|AF151810_1 CGI-52 protein [Homo sapiens], gi|15022799|ref|NP_006636.1| STAR...
297.0 [0..1] [291..69]
gi|62739256 - gi|62739256|gb|AAH94007.1| START domain containing 10 [Mus musculus]
289.0 [0..1] [283..54]
gi|76636043 - gi|76636043|ref|XP_592504.2| PREDICTED: similar to START domain containing 10 [Bos taurus]
287.0 [0..1] [291..150]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKPAASTEP QGSRPALGRE SVQVPDDQDF RSFRSECEAE VGWNLTYSKA GVSVWVQAVE  60
   61 MDRTLHKIKC RMECCDVPAE TLYDVLHDIE YRKKWDSNVI ETFDIARLTV NADVGYYSWR 120
  121 CPKPLKNRDV ITLRSWLPMG ADYIIMNYSV KHPKYPPRKD LVRAVSIQTG YLIQSTGPKS 180
  181 CVITYLAQVD PKGSLPKWVV NKSSQFLAPK AMKKMYKACI KYPEWKQKHQ PHFKPWLHPE 240
  241 QSPLPSLALS ELSVQHADSL ENIDESAVTE SREERAGGAG GEGSDDDTSL T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 1ln1A
Description: Phosphatidylcholine transfer protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 5.13837461289632 bayes_pls_golite062009
lipid transporter activity 3.89798461945498 bayes_pls_golite062009
phosphatidylinositol transporter activity 2.88424241201993 bayes_pls_golite062009
sterol binding 1.69869946950041 bayes_pls_golite062009
phosphatidylcholine transmembrane transporter activity 1.49746922653653 bayes_pls_golite062009
cholesterol binding 1.2916246557678 bayes_pls_golite062009
transporter activity 1.0230789944073 bayes_pls_golite062009
binding 0.943118991866496 bayes_pls_golite062009
substrate-specific transporter activity 0.711522470867323 bayes_pls_golite062009
lipid binding 0.144022082146249 bayes_pls_golite062009
protein binding 0.120309486759405 bayes_pls_golite062009
steroid binding 0.109277325408336 bayes_pls_golite062009
catalytic activity 0.0116392906163881 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle