YRC Public Data Repository - Protein Structure Prediction

Protein:	ARPC3_MOUSE
Organism:	Mus musculus
Length:	178 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARPC3_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|73994595 - gi\|73994595\|ref\|XP_534672.2\| PREDICTED: similar to Actin-related protein 2/3 complex subunit 3 (ARP2... gi\|195562227, gi... - gi\|195562227\|gb\|ACG50183.1\| actin related protein 2/3 complex subunit 3 [Sus scrofa], gi\|194042944\|r... gi\|109098698 - gi\|109098698\|ref\|XP_001107191.1\| PREDICTED: actin related protein 2/3 complex, subunit 3, 21kDa isof... ARPC3_BOVIN - Actin-related protein 2/3 complex subunit 3 OS=Bos taurus GN=ARPC3 PE=1 SV=3 ARPC3 - actin related protein 2/3 complex, subunit 3, 21kDa gi\|149720678 - gi\|149720678\|ref\|XP_001495332.1\| PREDICTED: similar to Actin-related protein 2/3 complex subunit 3 (... gi\|114576474 - gi\|114576474\|ref\|XP_001147520.1\| PREDICTED: similar to p21-Arc isoform 2 [Pan troglodytes] ENSCJAT000000440... - null, null	353.0	[0..1]	[178..1]
gi\|62901838 - gi\|62901838\|gb\|AAY18870.1\| p21-Arc [synthetic construct]	353.0	[0..2]	[178..13]
gi\|157786926, gi... - gi\|183986078\|gb\|AAI66554.1\| Actin related protein 2/3 complex, subunit 3 [Rattus norvegicus], gi\|157...	352.0	[0..1]	[178..1]
gi\|50756357 - gi\|50756357\|ref\|XP_415128.1\| PREDICTED: similar to p21-Arc [Gallus gallus]	351.0	[0..1]	[178..1]
gi\|33416674, gi\|... - gi\|33416674\|gb\|AAH56034.1\| Arpc3-prov protein [Xenopus laevis], gi\|148227376\|ref\|NP_001080054.1\| act...	347.0	[0..1]	[178..1]
gi\|68396839, gi\|... - gi\|68396839\|ref\|XP_696160.1\| PREDICTED: similar to actin related protein 2/3 complex, subunit 3 [Dan...	343.0	[0..1]	[178..1]
gi\|73994597 - gi\|73994597\|ref\|XP_861523.1\| PREDICTED: similar to Actin-related protein 2/3 complex subunit 3 (ARP2...	343.0	[0..1]	[171..1]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAYHSSLMD PDTKLIGNMA LLPLRSQFKG PAPRETKDTD IVDEAIYYFK ANVFFKNYEI  60
   61 KNEADRTLIY ITLYISECLK KLQKCNSKSQ GEKEMYTLGI TNFPIPGEPG FPLNAIYAKP 120
  121 ASKQEDEMMR AYLQQLRQET GLRLCEKVFD PQSDKPSKWW TCFVKRQFMN KSLSGPGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.0
Match:	1k8kE
Description:	Arp2/3 complex 21 kDa subunit ARPC3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	5.63989846641024	bayes_pls_golite062009
cytoskeletal protein binding	4.21664682046338	bayes_pls_golite062009
actin filament binding	3.53574857524507	bayes_pls_golite062009
structural constituent of cytoskeleton	2.90019731783322	bayes_pls_golite062009
binding	1.94576284584165	bayes_pls_golite062009
protein binding	0.756249220099259	bayes_pls_golite062009
structural molecule activity	0.662672430262145	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: