YRC Public Data Repository - Protein Structure Prediction

Protein:	NEP1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	359 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEP1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|71024225, gi\|... - gi\|71024225\|ref\|XP_762342.1\| hypothetical protein UM06195.1 [Ustilago maydis 521], ref\|XP_403810.1\| ...	385.0	[0..28]	[359..45]
gi\|46435312, gi\|... - gi\|68484534\|ref\|XP_713798.1\| hypothetical protein CaO19.665 [Candida albicans SC5314], gi\|68484455\|r... orf19.665, orf19... - NEP1 CGDID:CAL0001059 Assembly 19, Contig19-10064 (27357, 26554) CDS, reverse complemented, translat...	378.0	[0..99]	[358..13]
NEP1_CANAX - Ribosomal RNA small subunit methyltransferase NEP1 OS=Candida albicans GN=NEP1 PE=3 SV=1	371.0	[0..96]	[358..2]
gi\|27802999 - gi\|27802999\|emb\|CAD60702.1\| unnamed protein product [Podospora anserina]	365.0	[0..116]	[359..3]
gi\|32421521, gi\|... - gi\|32421521\|ref\|XP_331204.1\| hypothetical protein [Neurospora crassa], gi\|28920855\|gb\|EAA30197.1\| hy... gi\|85067694 - gi\|85067694\|ref\|XP_959433.1\| hypothetical protein [Neurospora crassa OR74A]	364.0	[0..116]	[359..10]
EMG1 - Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRN... gi\|151941029 - gi\|151941029\|gb\|EDN59409.1\| conserved protein [Saccharomyces cerevisiae YJM789] NEP1_YEAST - Ribosomal RNA small subunit methyltransferase NEP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /... gi\|190405254 - gi\|190405254\|gb\|EDV08521.1\| nucleolar essential protein 1 [Saccharomyces cerevisiae RM11-1a] gi\|207342990 - gi\|207342990\|gb\|EDZ70592.1\| YLR186Wp-like protein [Saccharomyces cerevisiae AWRI1631]	364.0	[0..113]	[359..5]
gi\|44985345 - gi\|44985345\|gb\|AAS54058.1\| AFR686Cp [Ashbya gossypii ATCC 10895] gi\|44985345, gi\|... - gi\|45199205\|ref\|NP_986234.1\| AFR686Cp [Ashbya gossypii ATCC 10895], gi\|44985345\|gb\|AAS54058.1\| AFR68...	363.0	[0..113]	[359..5]
gi\|49655584 - gi\|49655584\|emb\|CAG88158.1\| DEHA2E14036p [Debaryomyces hansenii] gi\|49655584, gi\|... - gi\|50422679\|ref\|XP_459916.1\| hypothetical protein DEHA0E14597g [Debaryomyces hansenii CBS767], gi\|49...	362.0	[0..127]	[358..15]
gi\|49641414 - gi\|49641414\|emb\|CAH01132.1\| KLLA0C01914p [Kluyveromyces lactis] gi\|49641414, gi\|... - gi\|50304651\|ref\|XP_452281.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641414\|emb\|CAH0113...	360.0	[0..119]	[359..10]

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Predicted Domain #1

Region A:
Residues: [1-88]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTYSKRKSR GSLEVSEKTN QPKFIKRSQS SETITSGETA SELMQDEKEQ SNGAVGSIED  60
   61 EELQRLRENQ ASVEALSKKP ESIDRELG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [89-359]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEALEIDNVV KSDEEKEDPN GASSKTVKAR PLPAGSVHRV TTHMAPIPAR SIGSHDTTTQ  60
   61 RLIVVLDQAC LEIYKVGKAK DAKYQLLNCD DHQGILKKLN RNIAQARPDI THQCLLTLLD 120
  121 SPLNKAGRLQ VYIHTAKKVL IEVNPSVRIP RTFKRFSGLM VQLLHKLSIR SVNGNEKLLK 180
  181 VIKNPVTDYL PPNCRKATLS FDAPTVPPRK YLETLQPNQS VCIAIGAMAH GPDDFSDGWV 240
  241 DEKISISDYP LSASIACSKF LHSMEDFLGI V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	101.0
Match:	2v3kA
Description:	No description for 2v3kA was found.

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	3.73300070859272	bayes_pls_golite062009
tRNA methyltransferase activity	2.75506106783732	bayes_pls_golite062009
methyltransferase activity	2.52574509568717	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	2.44351066049012	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.00166711852993	bayes_pls_golite062009
RNA binding	1.99948490385053	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	1.9680534181971	bayes_pls_golite062009
rRNA methyltransferase activity	1.94772102267592	bayes_pls_golite062009
transferase activity	1.19303525702973	bayes_pls_golite062009
binding	1.07947949398964	bayes_pls_golite062009
nucleic acid binding	0.987186921436979	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.425953878527171	bayes_pls_golite062009
protein binding	0.303628351374506	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: