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View Structure Prediction Details

Protein: gi|19263324, gi|...
Organism: Mus musculus
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|19263324, gi|....

Description E-value Query
Range
Subject
Range
gi|431451, gi|38... - pir||B53014 chloride channel protein I-Cln - rat, gi|431451|gb|AAC37642.1| regulatory protein, gi|38...
362.0 [0..1] [241..1]
gi|1060971 - gi|1060971|dbj|BAA05069.1| chloride channel [Oryctolagus cuniculus]
352.0 [0..5] [241..16]
ICLN_MOUSE - Methylosome subunit pICln OS=Mus musculus GN=Clns1a PE=1 SV=1
352.0 [0..6] [241..1]
gi|54696674, gi|... - gi|61366711|gb|AAX42897.1| chloride channel nucleotide-sensitive 1A [synthetic construct], gi|608275...
341.0 [0..6] [241..1]
CLNS1A - chloride channel, nucleotide-sensitive, 1A
gi|114639482 - gi|114639482|ref|XP_001175051.1| PREDICTED: chloride channel, nucleotide-sensitive, 1A isoform 2 [Pa...
gi|61356894, gi|... - gi|61358209|gb|AAX41526.1| chloride channel nucleotide-sensitive 1A [synthetic construct], gi|613568...
341.0 [0..6] [241..1]
ICLN_CANLF - Methylosome subunit pICln OS=Canis lupus familiaris GN=CLNS1A PE=1 SV=1
339.0 [0..6] [241..1]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSPAMSFLK SFPPPGSADG LRLQQPDTEA VLNGKGLGTG TLYIAESRLS WLDGSGLGFS  60
   61 LEYPTISLHA VSRDPNAYPQ EHLYVMVNAK LGEESKEPLS DEDEEDNDDV EPISEFRFVP 120
  121 SDKSALEAMF TAMCECQALH PDPEDEDSDD YDGEEYDVEA HEQGQGD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 1zyiA
Description: Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and rna splicing
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [168-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPTFYTYEEG LSHLTAEGQA TLERLEGMLS QSVSSQYNMA GVRTEDSVRN YEDGMEVETT  60
   61 PTVAGQFEDA DVDH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle