YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229681138, gi...
Organism:	Yersinia pestis Nepal516
Length:	145 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229681138, gi....

Description	E-value	Query Range	Subject Range
gi\|51588485, gi\|... - gi\|51595203\|ref\|YP_069394.1\| thioredoxin 2 [Yersinia pseudotuberculosis IP 32953], gi\|51588485\|emb\|C... Q66E40\|Q66E40_YERPS - Thioredoxin 2, redox factor - Yersinia pseudotuberculosis	2.0E-40	[1..145]	[1..145]
gi\|110616074, gi... - gi\|110806526\|ref\|YP_690046.1\| thioredoxin 2 [Shigella flexneri 5 str. 8401], gi\|110616074\|gb\|ABF0474... gi\|83570819, gi\|... - gi\|83570819\|ref\|ZP_00922262.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Shigella dysente... gi\|83586766, gi\|... - gi\|83586766\|ref\|ZP_00925397.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|91211910, gi\|... - gi\|91211910\|ref\|YP_541896.1\| thioredoxin 2 [Escherichia coli UTI89], gi\|91073484\|gb\|ABE08365.1\| puta... gi\|188014000, gi... - gi\|188014000\|gb\|EDU52122.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4113], gi\|16875207... gi\|15832702, gi\|... - gi\|15832702\|ref\|NP_311475.1\| thioredoxin 2 [Escherichia coli O157:H7 str. Sakai], gi\|13362919\|dbj\|BA... gi\|168757752, gi... - gi\|189355318\|gb\|EDU73737.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4401], gi\|16875775... gi\|110642744, gi... - gi\|110642744\|ref\|YP_670474.1\| thioredoxin 2 [Escherichia coli 536], gi\|110344336\|gb\|ABG70573.1\| thio... gi\|189365098, gi... - gi\|189365098\|gb\|EDU83514.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4501], gi\|16876502... gi\|195936730 - gi\|195936730\|ref\|ZP_03082112.1\| thioredoxin 2 [Escherichia coli O157:H7 str. EC4024] gi\|208729251, gi... - gi\|208809450\|ref\|ZP_03251787.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4206], gi\|2087... gi\|208735788, gi... - gi\|208814511\|ref\|ZP_03255840.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4045], gi\|2087... gi\|208821538, gi... - gi\|208821538\|ref\|ZP_03261858.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4042], gi\|2087... gi\|209396514, gi... - gi\|209396514\|ref\|YP_002272057.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4115], gi\|209... gi\|209920062, gi... - gi\|209920062\|ref\|YP_002294146.1\| thioredoxin 2 [Escherichia coli SE11], gi\|209913321\|dbj\|BAG78395.1\|... gi\|215487925, gi... - gi\|215487925\|ref\|YP_002330356.1\| thioredoxin 2 [Escherichia coli O127:H6 str. E2348/69], gi\|21526599... gi\|217327645, gi... - gi\|217327645\|ref\|ZP_03443728.1\| putative thioredoxin [Escherichia coli O157:H7 str. TW14588], gi\|217... gi\|189362197, gi... - gi\|189362197\|gb\|EDU80616.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4486], gi\|16876868... gi\|168773488, gi... - gi\|187770735\|gb\|EDU34579.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4196], gi\|16877348... gi\|189003461, gi... - gi\|189003461\|gb\|EDU72447.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC4076], gi\|16877856... gi\|189370141, gi... - gi\|189370141\|gb\|EDU88557.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC869], gi\|168790384... gi\|168801702, gi... - gi\|189376187\|gb\|EDU94603.1\| putative thioredoxin [Escherichia coli O157:H7 str. EC508], gi\|168801702... gi\|169754063, gi... - gi\|170019135\|ref\|YP_001724089.1\| thioredoxin 2 [Escherichia coli ATCC 8739], gi\|169754063\|gb\|ACA7676... gi\|169890026, gi... - gi\|170082191\|ref\|YP_001731511.1\| thioredoxin 2 [Escherichia coli str. K-12 substr. DH10B], gi\|169890... gi\|170680235, gi... - gi\|170680235\|ref\|YP_001744771.1\| putative thioredoxin [Escherichia coli SMS-3-5], gi\|170517953\|gb\|AC... THIO2_ECOL6 - Thioredoxin-2 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=trxC PE=3 SV=1 gi\|238901747, gi... - gi\|238901747\|ref\|YP_002927543.1\| thioredoxin 2 [Escherichia coli BW2952], gi\|238863645\|gb\|ACR65643.1... gi\|24053026, gi\|... - gi\|24113923\|ref\|NP_708433.1\| thioredoxin 2 [Shigella flexneri 2a str. 301], gi\|24053026\|gb\|AAN44140.... gi\|237705092, gi... - gi\|237705092\|ref\|ZP_04535573.1\| thioredoxin 2 [Escherichia sp. 3_2_53FAA], gi\|226901458\|gb\|EEH87717.... THIO2_ECO57 - Thioredoxin-2 OS=Escherichia coli O157:H7 GN=trxC PE=3 SV=1 gi\|227835968, gi... - gi\|227887618\|ref\|ZP_04005423.1\| protein-disulfide reductase [Escherichia coli 83972], gi\|227835968\|g... gi\|30063983, gi\|... - gi\|30063983\|ref\|NP_838154.1\| thioredoxin 2 [Shigella flexneri 2a str. 2457T], gi\|30042239\|gb\|AAP1796... gi\|12517004, gi\|... - gi\|15803110\|ref\|NP_289141.1\| thioredoxin 2 [Escherichia coli O157:H7 EDL933], gi\|12517004\|gb\|AAG5769... EG11887 - thioredoxin 2 / Thioredoxin 2, zinc-binding; Trx2 THI2_ECOLI, THIO... - Thioredoxin 2 (EC 1.8.1.8) (Protein-disulfide reductase) (Disulfide reductase) (Trx2) - Escherichia ... THIO2_ECOL6 - Thioredoxin-2 OS=Escherichia coli O6 GN=trxC PE=3 SV=1 THIO2_SHIFL - Thioredoxin-2 OS=Shigella flexneri GN=trxC PE=3 SV=1 gi\|117624804, gi... - gi\|117624804\|ref\|YP_853717.1\| thioredoxin 2 [Escherichia coli APEC O1], gi\|115513928\|gb\|ABJ02003.1\| ... gi\|124499835, gi... - gi\|124529528\|ref\|ZP_01700498.1\| thioredoxin [Escherichia coli B], gi\|124499835\|gb\|EAY47317.1\| thiore... gi\|254794534, gi... - gi\|254794534\|ref\|YP_003079371.1\| thioredoxin 2 [Escherichia coli O157:H7 str. TW14359], gi\|254593934... gi\|253974458, gi... - gi\|254162557\|ref\|YP_003045665.1\| thioredoxin 2 [Escherichia coli B str. REL606], gi\|253974458\|gb\|ACT... gi\|253323562, gi... - gi\|254289318\|ref\|YP_003055066.1\| thioredoxin 2 [Escherichia coli BL21(DE3)], gi\|253978625\|gb\|ACT4429... gi\|242378182, gi... - gi\|251785909\|ref\|YP_003000213.1\| hypothetical protein B21_02440 [Escherichia coli BL21], gi\|24237818... EG11887 - thioredoxin 2 / Thioredoxin 2, zinc-binding; Trx2 gi\|218547891, gi... - gi\|218547891\|ref\|YP_002381682.1\| thioredoxin 2 [Escherichia fergusonii ATCC 35469], gi\|218355432\|emb... gi\|218555166, gi... - gi\|218555166\|ref\|YP_002388079.1\| thioredoxin 2 [Escherichia coli IAI1], gi\|218361934\|emb\|CAQ99535.1\|... gi\|218559504, gi... - gi\|218559504\|ref\|YP_002392417.1\| thioredoxin 2 [Escherichia coli S88], gi\|218366273\|emb\|CAR04020.1\| ... gi\|218352943, gi... - gi\|218696211\|ref\|YP_002403878.1\| thioredoxin 2 [Escherichia coli 55989], gi\|218352943\|emb\|CAU98742.1... gi\|218701097, gi... - gi\|218701097\|ref\|YP_002408726.1\| thioredoxin 2 [Escherichia coli IAI39], gi\|218371083\|emb\|CAR18912.1... gi\|82778010, gi\|... - gi\|82778010\|ref\|YP_404359.1\| thioredoxin 2 [Shigella dysenteriae Sd197], gi\|81242158\|gb\|ABB62868.1\| ... gi\|85675470, gi\|... - gi\|89109388\|ref\|AP_003168.1\| thioredoxin 2 [Escherichia coli str. K-12 substr. W3110], gi\|85675470\|d... gi\|75513192, gi\|... - gi\|75513192\|ref\|ZP_00735634.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|73856622, gi\|... - gi\|74313145\|ref\|YP_311564.1\| thioredoxin 2 [Shigella sonnei Ss046], gi\|73856622\|gb\|AAZ89329.1\| putat... gi\|157162062, gi... - gi\|75196601\|ref\|ZP_00706671.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|194412683, gi... - gi\|75209515\|ref\|ZP_00709740.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|187730887, gi... - gi\|75178186\|ref\|ZP_00698245.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Shigella boydii ... gi\|157156661, gi... - gi\|75187335\|ref\|ZP_00700602.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|192958245, gi... - gi\|75237672\|ref\|ZP_00721688.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|75258007, gi\|... - gi\|75258007\|ref\|ZP_00729481.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|191167976, gi... - gi\|75228843\|ref\|ZP_00715444.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|191174032, gi... - gi\|75237399\|ref\|ZP_00721434.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli...	9.0E-40	[1..139]	[1..139]
gi\|81246448, gi\|... - gi\|82545037\|ref\|YP_408984.1\| thioredoxin 2 [Shigella boydii Sb227], gi\|81246448\|gb\|ABB67156.1\| putat...	1.0E-39	[1..139]	[1..139]
gi\|194710494, gi... - gi\|194734992\|ref\|YP_002115661.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar S... gi\|197211460, gi... - gi\|197247757\|ref\|YP_002147553.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar A... gi\|194449202, gi... - gi\|194449202\|ref\|YP_002046658.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Heidelbe... gi\|194456948, gi... - gi\|194470584\|ref\|ZP_03076568.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Ke... gi\|16765969, gi\|... - gi\|16765969\|ref\|NP_461584.1\| thioredoxin 2 [Salmonella typhimurium LT2], gi\|16421199\|gb\|AAL21543.1\| ... gi\|205340545, gi... - gi\|205340545\|gb\|EDZ27309.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Weltev... gi\|238912714 - gi\|238912714\|ref\|ZP_04656551.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Tennessee... gi\|194405008, gi... - gi\|194446345\|ref\|YP_002041916.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar N... gi\|168262181, gi... - gi\|205349283\|gb\|EDZ35914.1\| thioredoxin [Salmonella enterica subsp. enterica serovar Hadar str. RI_0... gi\|195628856, gi... - gi\|195628856\|gb\|EDX48270.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Newpor... gi\|197288811, gi... - gi\|197288811\|gb\|EDY28184.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Schwar... gi\|168245087, gi... - gi\|205336127\|gb\|EDZ22891.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Heidel... gi\|205327358, gi... - gi\|205327358\|gb\|EDZ14122.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar 4,[5],... gi\|205333585, gi... - gi\|205333585\|gb\|EDZ20349.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Kentuc... gi\|161361995, gi... - gi\|161612631\|ref\|YP_001586596.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Paratyph... gi\|167553663, gi... - gi\|205321936\|gb\|EDZ09775.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Saintp... gi\|204929715, gi... - gi\|204929715\|ref\|ZP_03220789.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Ja... gi\|224469031, gi... - gi\|224584504\|ref\|YP_002638302.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Paratyph... gi\|198242015, gi... - gi\|198242015\|ref\|YP_002216664.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar D... gi\|199605943, gi... - gi\|200388845\|ref\|ZP_03215457.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Vi... gi\|197242875, gi... - gi\|197264620\|ref\|ZP_03164694.1\| putative thioredoxin [Salmonella enterica subsp. enterica serovar Sa... gi\|197361463, gi... - gi\|197361463\|ref\|YP_002141099.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Paratyph... lcl\|NC_016856.1_... - [gene=trxC] [protein=thioredoxin 2] [protein_id=YP_005238771.1] [location=2842488..2842907] gi\|62128857, gi\|... - gi\|62181224\|ref\|YP_217641.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Choleraesuis... gi\|56126785, gi\|... - gi\|56412528\|ref\|YP_149603.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Paratyphi A ...	1.0E-39	[1..139]	[1..139]
gi\|214000651 - gi\|214000651\|ref\|ZP_03411386.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213861078 - gi\|213861078\|ref\|ZP_03385782.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213646340 - gi\|213646340\|ref\|ZP_03376393.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213615730 - gi\|213615730\|ref\|ZP_03371556.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|16761507 - gi\|16761507\|ref\|NP_457124.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str. C... gi\|16503808, gi\|... - gi\|25282764\|pir\|\|AB0831 thioredoxin 2 [imported] - Salmonella enterica subsp. enterica serovar Typhi... gi\|29136421, gi\|... - gi\|29140796\|ref\|NP_804138.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str. T... gi\|213026637 - gi\|213026637\|ref\|ZP_03341084.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213583758 - gi\|213583758\|ref\|ZP_03365584.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213425262 - gi\|213425262\|ref\|ZP_03358012.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213417426 - gi\|213417426\|ref\|ZP_03350568.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213161474 - gi\|213161474\|ref\|ZP_03347184.1\| thioredoxin 2 [Salmonella enterica subsp. enterica serovar Typhi str...	6.0E-39	[1..139]	[1..139]
gi\|71906567, gi\|... - gi\|71906567\|ref\|YP_284154.1\| thioredoxin [Dechloromonas aromatica RCB], gi\|71846188\|gb\|AAZ45684.1\| T...	2.0E-38	[1..139]	[5..144]
gi\|90410072, gi\|... - gi\|90410072\|ref\|ZP_01218089.1\| putative thioredoxin 2 [Photobacterium profundum 3TCK], gi\|90329425\|g...	4.0E-38	[1..141]	[4..144]
gi\|50122438, gi\|... - gi\|50122438\|ref\|YP_051605.1\| thioredoxin 2 [Pectobacterium atrosepticum SCRI1043], gi\|49612964\|emb\|C...	6.0E-38	[1..139]	[1..139]
gi\|28809273, gi\|... - gi\|28900827\|ref\|NP_800482.1\| thioredoxin 2 [Vibrio parahaemolyticus RIMD 2210633], gi\|28809273\|dbj\|B... gi\|28809273 - gi\|28809273\|dbj\|BAC62315.1\| thioredoxin 2 [Vibrio parahaemolyticus RIMD 2210633]	8.0E-38	[3..141]	[6..144]
gi\|116186708, gi... - gi\|75857535\|ref\|ZP_00765149.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Vibrio sp. Ex25]...	1.0E-37	[3..141]	[6..144]

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Predicted Domain #1

Region A:
Residues: [1-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTVCTACMA TNRLPEERID DGAKCGRCGH SLFDGEVINA TAETLDKLLQ DDLPMVIDFW  60
   61 APWCGPCRSF APIFAETAAE RAGKVRFVKV NTEAEPALST RFRIRSIPTI MLYRNGKMID 120
  121 MLNGAVPKAP FDNWLDEQLS RDPNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.0
Match:	1v98A
Description:	Crystal Structure Analysis of Thioredoxin from Thermus thermophilus
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits