YRC Public Data Repository - Protein Structure Prediction

Protein:	MOB3B_MOUSE
Organism:	Mus musculus
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOB3B_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|73975379 - gi\|73975379\|ref\|XP_539306.2\| PREDICTED: similar to Mps one binder kinase activator-like 1A (Mob1 hom...	362.0	[0..10]	[214..190]
gi\|74221345 - gi\|74221345\|dbj\|BAE42152.1\| unnamed protein product [Mus musculus]	354.0	[0..1]	[216..1]
gi\|149045612, gi... - gi\|62648790\|ref\|XP_345519.2\| PREDICTED: similar to Mob3b protein [Rattus norvegicus], gi\|157822781\|r... tr\|G3HJ34\|G3HJ34... - Mps one binder kinase activator-like 2B OS=Cricetulus griseus GN=I79_010668 PE=4 SV=1	353.0	[0..1]	[216..1]
MOB3B_BOVIN - MOB kinase activator 3B OS=Bos taurus GN=MOB3B PE=2 SV=1	353.0	[0..1]	[216..1]
gi\|208966788 - gi\|208966788\|dbj\|BAG73408.1\| MOB1, Mps One Binder kinase activator-like 2B [synthetic construct] MOBKL2B - MOB1, Mps One Binder kinase activator-like 2B (yeast) ENSCJAT00000036084 - null gi\|109111313 - gi\|109111313\|ref\|XP_001104813.1\| PREDICTED: similar to MOB1, Mps One Binder kinase activator-like 2B... gi\|114623999 - gi\|114623999\|ref\|XP_001154635.1\| PREDICTED: hypothetical protein [Pan troglodytes]	352.0	[0..1]	[216..1]
gi\|109103421 - gi\|109103421\|ref\|XP_001107567.1\| PREDICTED: similar to Mob4B protein [Macaca mulatta]	346.0	[0..10]	[214..50]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIALKQVFN KDKTFRPKRK FEPGTQRFEL HKRAQASLNS GVDLRAAVQL PNGEDQNDWV  60
   61 AVHVVDFFNR INLIYGTICE FCTERTCPVM SGGPKYEYRW QDDLKYKKPT ALPAPQYMNL 120
  121 LMDWIEVQIN NEDIFPTCVG VPFPKNFLQI CKKILCRLFR VFVHVYIHHF DRVIVMGAEA 180
  181 HVNTCYKHFY YFVTEMNLID RKELEPLKEM TTRMCH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.39794
Match:	1r3bA
Description:	Solution structure of xenopus laevis Mob1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.92301852481284	bayes_pls_golite062009
kinase regulator activity	1.89112613830997	bayes_pls_golite062009
enzyme regulator activity	1.85961781963242	bayes_pls_golite062009
protein binding	1.70532605681329	bayes_pls_golite062009
protein kinase regulator activity	1.22656624834768	bayes_pls_golite062009
enzyme activator activity	1.01199608762933	bayes_pls_golite062009
kinase activator activity	0.48120280834988	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: