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View Structure Prediction Details

Protein: IL20_MOUSE
Organism: Mus musculus
Length: 176 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL20_MOUSE.

Description E-value Query
Range
Subject
Range
IL10_SAISC - Interleukin-10 OS=Saimiri sciureus GN=IL10 PE=2 SV=1
209.0 [0..7] [176..3]
IL10_CALJA - Interleukin-10 OS=Callithrix jacchus GN=IL10 PE=2 SV=1
208.0 [0..7] [176..3]
IL10_HORSE - Interleukin-10 OS=Equus caballus GN=IL10 PE=2 SV=1
207.0 [0..7] [176..3]
IL10_RABIT - Interleukin-10 OS=Oryctolagus cuniculus GN=IL10 PE=2 SV=1
206.0 [0..6] [176..2]
gi|73960666 - gi|73960666|ref|XP_851510.1| PREDICTED: similar to interleukin 20 precursor [Canis familiaris]
205.0 [0..1] [175..1]
gi|114572230 - gi|114572230|ref|XP_001165088.1| PREDICTED: interleukin 19 isoform 1 [Pan troglodytes]
199.0 [0..1] [174..39]
gi|15266466, gi|... - gi|15266466|gb|AAK91776.1| interleukin 19 [Homo sapiens], gi|119613928|gb|EAW93522.1| interleukin 19...
199.0 [0..1] [174..39]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGFGLAFGL FSAVGFLLWT PLTGLKTLHL GSCVITANLQ AIQKEFSEIR DSVQAEDTNI  60
   61 DIRILRTTES LKDIKSLDRC CFLRHLVRFY LDRVFKVYQT PDHHTLRKIS SLANSFLIIK 120
  121 KDLSVCHSHM ACHCGEEAME KYNQILSHFI ELELQAAVVK ALGELGILLR WMEEML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.522879
Match: 1n1fA
Description: Interleukin-19
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine receptor binding 6.47223189691244 bayes_pls_golite062009
receptor binding 5.3304255990112 bayes_pls_golite062009
cytokine activity 4.48255796229335 bayes_pls_golite062009
growth factor activity 3.72884804690203 bayes_pls_golite062009
protein binding 3.26483713001551 bayes_pls_golite062009
binding 2.48265117231403 bayes_pls_golite062009
prolactin receptor binding 2.45721634350294 bayes_pls_golite062009
interleukin-6 receptor binding 2.37535614986843 bayes_pls_golite062009
hormone activity 2.25587306265428 bayes_pls_golite062009
ciliary neurotrophic factor receptor binding 1.85526699537139 bayes_pls_golite062009
growth hormone activity 1.79923161766484 bayes_pls_golite062009
interleukin-27 binding 1.07353685869636 bayes_pls_golite062009
catalytic activity 0.246169290135575 bayes_pls_golite062009
erythropoietin receptor binding 0.225986442324192 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle