YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|109088233
Organism:	Macaca mulatta
Length:	342 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|109088233.

Description	E-value	Query Range	Subject Range
PRP18_BOVIN - Pre-mRNA-splicing factor 18 OS=Bos taurus GN=PRPF18 PE=2 SV=1	0.0	[1..342]	[1..342]
PRP18_PONAB - Pre-mRNA-splicing factor 18 OS=Pongo abelii GN=PRPF18 PE=2 SV=1 gi\|55726471 - gi\|55726471\|emb\|CAH90004.1\| hypothetical protein [Pongo abelii]	0.0	[1..342]	[1..342]
PRP18_MOUSE - Pre-mRNA-splicing factor 18 OS=Mus musculus GN=Prpf18 PE=1 SV=1	0.0	[1..342]	[1..342]
gi\|73949024 - gi\|73949024\|ref\|XP_535182.2\| PREDICTED: similar to Pre-mRNA splicing factor 18 (PRP18 homolog) (hPRP...	0.0	[1..342]	[1..342]
PRP18_RAT - Pre-mRNA-splicing factor 18 OS=Rattus norvegicus GN=Prpf18 PE=2 SV=1	0.0	[1..342]	[1..342]
gi\|109088231 - gi\|109088231\|ref\|XP_001086532.1\| PREDICTED: PRP18 pre-mRNA processing factor 18 homolog isoform 2 [M... gi\|114629420 - gi\|114629420\|ref\|XP_001142338.1\| PREDICTED: PRP18 pre-mRNA processing factor 18 homolog isoform 3 [P...	0.0	[1..342]	[1..351]
gi\|50731328 - gi\|50731328\|ref\|XP_417229.1\| PREDICTED: similar to hPrp18 [Gallus gallus]	0.0	[1..342]	[1..342]
gi\|114629430 - gi\|114629430\|ref\|XP_001142250.1\| PREDICTED: PRP18 pre-mRNA processing factor 18 homolog isoform 2 [P... gi\|119606689 - gi\|119606689\|gb\|EAW86283.1\| PRP18 pre-mRNA processing factor 18 homolog (yeast), isoform CRA_d [Homo...	0.0	[18..342]	[3..327]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDILKSEILR KRQLVEDRNL LVENKKYFKR SELAKKEEEA YFERCGYKIQ PKEEDQKPLT  60
   61 SSNPVLELEL AEEKLPMTLS RQEVIRRLRE RGEPIRLFGE TDYDAFQRLR KIEILTPEVN 120
  121 KGLRNDLKAA LDKIDQQYLN EIVGGQEPGE EDT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.30103
Match:	2dk4A
Description:	No description for 2dk4A was found.

Predicted Domain #2

Region A:
Residues: [154-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNDLKVHEEN TTIEELEALG ESLGKGDDHK DMDIITKFLK FLLGVWAKEL NAREDYVKRS  60
   61 VQGKLNSATQ KQTESYLRPL FRKLRKRNLP ADIKESITDI IKFMLQREYV KANDAYLQMA 120
  121 IGNAPWPIGV TMVGIHARTG REKIFSKHVA HVLNDETQRK YIQGLKRLMT ICQKHFPTDP 180
  181 SKCVEYNAL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.0
Match:	1dvkA
Description:	Functional domain of the splicing factor Prp18
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
	8.4933513491836	bayes_pls_golite062009
second spliceosomal transesterification activity	5.51692977589724	bayes_pls_golite062009
catalytic activity	0.60409960326459	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: