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View Structure Prediction Details

Protein: RNC_STRPC
Organism: Streptococcus pyogenes MGAS9429
Length: 230 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNC_STRPC.

Description E-value Query
Range
Subject
Range
RNC_STRTD - Ribonuclease 3 OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) GN=rnc PE=3 SV=1
236.0 [0..1] [228..1]

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Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQLEELLST SFDIQFNDLT LLETAFTHTS YANEHRLLNV SHNERLEFLG DAVLQLIISE  60
   61 YLFAKYPKKT EGDMSKLRSM IVREESLAGF SRFCSFDAYI KLGKGEEKSG GRRRDTILGD 120
  121 LFEAFLGALL LDKGIDAVRR FLKQVMIPQV EKGNFERVKD YKTCLQEFLQ TKGDVAIDYQ 180
  181 VISEKGPAHA KQFEVSIVVN GAVLSKGLGK SKKLAEQDAA KNALAQLSEV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.221849
Match: 1o0wA
Description: RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.103878681691 bayes_pls_golite062009
endoribonuclease activity 2.02847548000256 bayes_pls_golite062009
endonuclease activity 1.52328576888271 bayes_pls_golite062009
binding 1.36306903445995 bayes_pls_golite062009
nucleic acid binding 1.33734225890407 bayes_pls_golite062009
double-stranded RNA binding 0.80785216315429 bayes_pls_golite062009
catalytic activity 0.328884095744829 bayes_pls_golite062009
protein binding 0.018276859224266 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle