YRC Public Data Repository - Protein Structure Prediction

Protein:	MTHFS_MOUSE
Organism:	Mus musculus
Length:	203 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTHFS_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|74196670 - gi\|74196670\|dbj\|BAE34435.1\| unnamed protein product [Mus musculus]	226.0	[0..1]	[203..1]
gi\|56541204, gi\|... - gi\|57164141\|ref\|NP_001009349.1\| 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate c...	225.0	[0..1]	[203..1]
gi\|114658448 - gi\|114658448\|ref\|XP_001154891.1\| PREDICTED: 5,10-methenyltetrahydrofolate synthetase (5-formyltetrah...	220.0	[0..1]	[203..1]
MTHFS - 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)	217.0	[0..1]	[203..1]
gi\|73951703 - gi\|73951703\|ref\|XP_852666.1\| PREDICTED: similar to 5-formyltetrahydrofolate cyclo-ligase (5,10-methe...	210.0	[0..10]	[202..11]
gi\|92096592, gi\|... - gi\|92096592\|gb\|AAI14727.1\| 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-...	208.0	[0..2]	[200..3]
gi\|59712711, gi\|... - gi\|59712711\|ref\|YP_205487.1\| ligase [Vibrio fischeri ES114], gi\|59480812\|gb\|AAW86599.1\| predicted li...	208.0	[0..8]	[201..2]
gi\|192930785, gi... - gi\|193063508\|ref\|ZP_03044597.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli E22], gi\|... gi\|208725708, gi... - gi\|208805907\|ref\|ZP_03248244.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|189403793, gi... - gi\|189403793\|ref\|ZP_02785050.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|38704126 - gi\|38704126\|ref\|NP_311809.2\| putative ligase [Escherichia coli O157:H7] gi\|189404764, gi... - gi\|189404764\|ref\|ZP_02810768.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|209160736, gi... - gi\|209399336\|ref\|YP_002272387.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 ... gi\|217319900, gi... - gi\|217327533\|ref\|ZP_03443616.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|208735489, gi... - gi\|208814212\|ref\|ZP_03255541.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|208819943, gi... - gi\|208819943\|ref\|ZP_03260263.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|170018843, gi... - gi\|170018843\|ref\|YP_001723797.1\| putative ligase [Escherichia coli ATCC 8739], gi\|169753771\|gb\|ACA76... gi\|194424183, gi... - gi\|83587693\|ref\|ZP_00926320.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli 101-... gi\|189401951, gi... - gi\|189401951\|ref\|ZP_02778860.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|194415490, gi... - gi\|75212474\|ref\|ZP_00712498.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli B171... gi\|189402865, gi... - gi\|189402865\|ref\|ZP_02791915.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|75228579, gi\|... - gi\|75228579\|ref\|ZP_00715208.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli B7A]... gi\|188024584, gi... - gi\|188024584\|ref\|ZP_02772628.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|192959432, gi... - gi\|75239520\|ref\|ZP_00723491.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli E110... gi\|189010397, gi... - gi\|189010397\|ref\|ZP_03006309.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|38704126 - gi\|38704126\|ref\|NP_311809.2\| putative ligase [Escherichia coli O157:H7 str. Sakai] gi\|33347709\|ref\|... - putative ligase [Escherichia coli K12], putative ligase [Escherichia coli K12], 5-formyltetrahydrofo...	208.0	[0..1]	[199..1]
gi\|27364918, gi\|... - gi\|27364918\|ref\|NP_760446.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio vulnificus CMCP6], gi\|273... gi\|37681033, gi\|... - gi\|37681033\|ref\|NP_935642.1\| 5-formyltetrahydrofolate cyclo-ligase [Vibrio vulnificus YJ016], gi\|371...	207.0	[0..6]	[199..2]

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Predicted Domain #1

Region A:
Residues: [1-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVTVNSAK RGLRAELKQR LRALSAEERL RQSLLLTQKV IAHNQYQNSK RISIFLSMQD  60
   61 EVETEVIIKD IFKQGKICFI PRYQFQSNHM DMVRLTSSEE IALLPKTSWN IHQPGEGDVR 120
  121 EEALSTGGLD LIFLPGLGFD KDGNRLGRGK GYYDTYLKRC VQHQEVKPYT MALAFKEQIC 180
  181 PQIPVDEHDM KVDEVLYEDS PAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.522879
Match:	1ydmA
Description:	X-Ray structure of Northeast Structural Genomics target SR44
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits