YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1742785, gi\|8...
Organism:	Escherichia coli str. K-12 substr. W3110
Length:	348 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1742785, gi|8....

Description	E-value	Query Range	Subject Range
gi\|62126962, gi\|... - gi\|62179329\|ref\|YP_215746.1\| 3-deoxy-7-phosphoheptulonate synthase [Salmonella enterica subsp. enter...	468.0	[0..2]	[347..46]
gi\|73854749, gi\|... - gi\|74311272\|ref\|YP_309691.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella sonnei Ss046], gi...	468.0	[0..2]	[347..3]
gi\|193069560, gi... - gi\|75235771\|ref\|ZP_00719926.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	468.0	[0..2]	[347..3]
gi\|50120320, gi\|... - gi\|50120320\|ref\|YP_049487.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Pectobacterium atrosepticu...	466.0	[0..2]	[347..3]
gi\|30040334, gi\|... - gi\|30062090\|ref\|NP_836261.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|24111977, gi\|... - gi\|24111977\|ref\|NP_706487.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|110614175, gi... - gi\|110804627\|ref\|YP_688147.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 5 str. ...	465.0	[0..2]	[347..3]
gi\|59713577, gi\|... - gi\|59713577\|ref\|YP_206352.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Vibrio fischeri ES114], gi...	465.0	[0..1]	[347..1]
AROG_ECO57 - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive OS=Escherichia coli O157:H7 GN=aroG PE=3 ... gi\|238859808, gi... - gi\|238900012\|ref\|YP_002925808.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|242376509, gi... - gi\|251784236\|ref\|YP_002998540.1\| hypothetical protein B21_00696 [Escherichia coli BL21], gi\|24237650... gi\|15800463, gi\|... - gi\|15800463\|ref\|NP_286475.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 E... gi\|253976912, gi... - gi\|254287605\|ref\|YP_003053353.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... AROG_ECOLI - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (EC 2.5.1.54) (Phospho-2-keto-3-deoxyhept... gi\|253972718, gi... - gi\|254160817\|ref\|YP_003043925.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|254591304, gi... - gi\|254791904\|ref\|YP_003076741.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|168750246, gi... - gi\|188015532\|gb\|EDU53654.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|1651339, gi\|8... - gi\|89107605\|ref\|AP_001385.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine rep... gi\|13360241, gi\|... - gi\|15830036\|ref\|NP_308809.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 s... gi\|168763344, gi... - gi\|189366448\|gb\|EDU84864.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168757043, gi... - gi\|189355850\|gb\|EDU74269.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|187768162, gi... - gi\|187768162\|gb\|EDU32006.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189363458, gi... - gi\|189363458\|gb\|EDU81877.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189373159, gi... - gi\|189373159\|gb\|EDU91575.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168779242, gi... - gi\|189002923\|gb\|EDU71909.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|81240176, gi\|... - gi\|82776028\|ref\|YP_402375.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella dysenteriae Sd197... gi\|217326155, gi... - gi\|217326155\|ref\|ZP_03442239.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|81244585, gi\|... - gi\|82543174\|ref\|YP_407121.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella boydii Sb227], gi... gi\|209917998, gi... - gi\|209917998\|ref\|YP_002292082.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli SE11]... gi\|192926766, gi... - gi\|75256338\|ref\|ZP_00728008.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|75511356, gi\|... - gi\|75511356\|ref\|ZP_00734041.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|218694171, gi... - gi\|218694171\|ref\|YP_002401838.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 55989... gi\|170020908, gi... - gi\|170020908\|ref\|YP_001725862.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli ATCC ... gi\|83584861, gi\|... - gi\|83584861\|ref\|ZP_00923520.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|168800814, gi... - gi\|189376981\|gb\|EDU95397.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|195936742 - gi\|195936742\|ref\|ZP_03082124.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H... gi\|170080414, gi... - gi\|170080414\|ref\|YP_001729734.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|194412266, gi... - gi\|75209077\|ref\|ZP_00709335.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208731490, gi... - gi\|208814842\|ref\|ZP_03256021.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|75228379, gi\|... - gi\|75228379\|ref\|ZP_00715027.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208808417, gi... - gi\|208808417\|ref\|ZP_03250754.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|187427742, gi... - gi\|75175250\|ref\|ZP_00695560.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|124531871, gi... - gi\|124531871\|ref\|ZP_01701970.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli B], gi... gi\|209400570, gi... - gi\|209400570\|ref\|YP_002269381.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia c... gi\|75194907, gi\|... - gi\|75194907\|ref\|ZP_00704977.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208737562, gi... - gi\|208822077\|ref\|ZP_03262396.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co...	465.0	[0..2]	[347..3]
gi\|157154975, gi... - gi\|75189768\|ref\|ZP_00703035.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	465.0	[0..2]	[347..3]
gi\|75237090, gi\|... - gi\|75237090\|ref\|ZP_00721144.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|110640955, gi... - gi\|110640955\|ref\|YP_668683.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 536], gi...	465.0	[0..2]	[347..3]
gi\|30749575, gi\|... - gi\|30749576\|pdb\|1N8F\|D Chain D, Crystal Structure Of E24q Mutant Of Phenylalanine-Regulated 3-Deoxy-...	465.0	[0..2]	[347..3]

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Predicted Domain #1

Region A:
Residues: [1-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRTDELRTA RIESLVTPAE LALRYPVTPG VATHVTDSRR RIEKILNGED KRLLVIIGPC  60
   61 SIHDLTAAME YATRLQSLRN QYQSRLEIVM RTYFEKPRTV VGWKGLISDP DLNGSYRVNH 120
  121 GLELARKLLL QVNELGVPTA TEFLDMVTGQ FIADLISWGA IGARTTESQI HREMASALSC 180
  181 PVGFKNGTDG NTRIAVDAIR AARASHMFLS PDKNGQMTIY QTSGNPYGHI IMRGGKKPNY 240
  241 HADDIAAACD TLHEFDLPEH LVVDFSHGNC QKQHRRQLEV CEDICQQIRN GSTAIAGIMA 300
  301 ESFLREGTQK IVGSQPLTYG QSITDPCLGW EDTERLVEKL ASAVDTRF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	132.0
Match:	1gg1A
Description:	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
dihydrodipicolinate synthase activity	1.2687335039487	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.719960432098845	bayes_pls_golite062009
oxo-acid-lyase activity	0.606352769346285	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
carbon-carbon lyase activity	0.36754360512349	bayes_pls_golite062009
3-deoxy-8-phosphooctulonate synthase activity	0.0356008407895519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: