YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|110807671, gi...
Organism:	Shigella flexneri 5 str. 8401
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|110807671, gi....

Description	E-value	Query Range	Subject Range
gi\|77958429, gi\|... - gi\|77958429\|ref\|ZP_00822462.1\| COG0566: rRNA methylases [Yersinia bercovieri ATCC 43970], gi\|2387840...	236.0	[0..1]	[228..1]
gi\|77976740, gi\|... - gi\|77976740\|ref\|ZP_00832213.1\| COG0566: rRNA methylases [Yersinia intermedia ATCC 29909], gi\|2387945...	235.0	[0..1]	[228..1]
gi\|77972419, gi\|... - gi\|77972419\|ref\|ZP_00827985.1\| COG0566: rRNA methylases [Yersinia frederiksenii ATCC 33641], gi\|2387...	235.0	[0..1]	[228..1]
gi\|238797645, gi... - gi\|77962009\|ref\|ZP_00825836.1\| COG0566: rRNA methylases [Yersinia mollaretii ATCC 43969], gi\|2387976...	235.0	[0..1]	[228..1]
gi\|165936350, gi... - gi\|89102581\|ref\|ZP_01175204.1\| COG0566: rRNA methylases [Yersinia pestis biovar Orientalis str. IP27... gi\|108781409, gi... - gi\|108809496\|ref\|YP_653412.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis Antiqua], gi\|10... gi\|229836148, gi... - gi\|229836148\|ref\|ZP_04456316.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Yersinia pestis Pestoides ... gi\|22124024, gi\|... - gi\|22124024\|ref\|NP_667447.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis KIM], gi\|2195676... gi\|229839886, gi... - gi\|229839886\|ref\|ZP_04460045.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Yersinia pestis biovar Ori... gi\|25331659 - pir\|\|AF0005 tRNA (guanosine-2'-O-)-methyltransferase (EC 2.1.1.34) [imported] - Yersinia pestis (str... gi\|229690278, gi... - gi\|229841968\|ref\|ZP_04462123.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Yersinia pestis biovar Ori... gi\|51594392, gi\|... - gi\|51594392\|ref\|YP_068583.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pseudotuberculosis IP 3... gi\|229678621, gi... - gi\|229904503\|ref\|ZP_04519614.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Yersinia pestis Nepal516],... Q66GE8\|Q66GE8_YERPS - TRNA (Guanosine-2'-O-)-methyltransferase - Yersinia pseudotuberculosis gi\|45434758, gi\|... - gi\|45439903\|ref\|NP_991442.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Microtus ... gi\|15978152, gi\|... - gi\|218927258\|ref\|YP_002345133.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis CO92], gi\|16... gi\|77630894, gi\|... - gi\|77630894\|ref\|ZP_00793480.1\| COG0566: rRNA methylases [Yersinia pseudotuberculosis IP 31758], gi\|1... gi\|167402131, gi... - gi\|167402131\|ref\|ZP_02307608.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Antiqu... gi\|166205088, gi... - gi\|166213686\|ref\|ZP_02239721.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Antiqu... gi\|167054333, gi... - gi\|167426644\|ref\|ZP_02318397.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Mediae... gi\|166963391, gi... - gi\|167419397\|ref\|ZP_02311150.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Orient... gi\|167468213 - gi\|167468213\|ref\|ZP_02332917.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis FV-1] gi\|150260899, gi... - gi\|150260899\|ref\|ZP_01917627.1\| tRNA (guanosine-2'-O-)-methyltransferase [Yersinia pestis CA88-4125]... gi\|145601108, gi... - gi\|145601108\|ref\|YP_001165184.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis Pestoides F]... gi\|165989610, gi... - gi\|166011464\|ref\|ZP_02232362.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Antiqu... gi\|77634084, gi\|... - gi\|77634084\|ref\|ZP_00796193.1\| COG0566: rRNA methylases [Yersinia pestis Angola], gi\|162419568\|ref\|Y... gi\|165926178, gi... - gi\|165926178\|ref\|ZP_02222010.1\| tRNA guanosine-2'-O-methyltransferase [Yersinia pestis biovar Orient...	233.0	[0..1]	[228..1]
gi\|91213169, gi\|... - gi\|91213169\|ref\|YP_543155.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli UTI89], gi\|9107... gi\|157078987, gi... - gi\|75188409\|ref\|ZP_00701676.1\| COG0566: rRNA methylases [Escherichia coli E24377A], gi\|157156957\|ref... gi\|115515047, gi... - gi\|117625923\|ref\|YP_859246.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli APEC O1], gi\|1... gi\|218560723, gi... - gi\|218560723\|ref\|YP_002393636.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli S88], gi\|21... gi\|218429498, gi... - gi\|218691934\|ref\|YP_002400146.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli ED1a], gi\|2... gi\|26110728, gi\|... - gi\|26250298\|ref\|NP_756338.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli CFT073], gi\|261...	230.0	[0..1]	[229..1]
gi\|75179690, gi\|... - gi\|75179690\|ref\|ZP_00699677.1\| COG0566: rRNA methylases [Shigella boydii BS512], gi\|187732340\|ref\|YP...	229.0	[0..1]	[229..1]
gi\|83571438, gi\|... - gi\|83571438\|ref\|ZP_00922878.1\| COG0566: rRNA methylases [Shigella dysenteriae 1012], gi\|194431220\|re...	228.0	[0..1]	[229..1]
gi\|170519543, gi... - gi\|170681825\|ref\|YP_001745951.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli SMS-3-5], g... gi\|218707285, gi... - gi\|218707285\|ref\|YP_002414804.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli UMN026], gi... gi\|110643892, gi... - gi\|110643892\|ref\|YP_671622.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli 536], gi\|11034... gi\|190909145, gi... - gi\|75242570\|ref\|ZP_00726314.1\| COG0566: rRNA methylases [Escherichia coli F11], gi\|191170337\|ref\|ZP_...	227.0	[0..1]	[229..1]
gi\|193070365, gi... - gi\|75234809\|ref\|ZP_00719112.1\| COG0566: rRNA methylases [Escherichia coli E110019], gi\|193070365\|ref...	227.0	[0..1]	[229..1]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPTRYARIC EMLARRQPDL TVCMEQVHKP HNVSAIIRTA DAVGVHEVHA VWPGSRMRTM  60
   61 ASAAAGSNSW VQVKTHRTIG DAVAHLKGQG MQILATHLSD NAVDFREIDY TRPTCILMGQ 120
  121 EKTGITQEAL ALADQDIIIP MIGMVQSLNV SVASALILYE AQRQRQNAGM YLRENSMLPE 180
  181 AEQQRLLFEG GYPVLAKVAK RKGLPYPHVN QQGEIEADAD WWATMQAAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.69897
Match:	1v2xA
Description:	TrmH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.77771076540343	bayes_pls_golite062009
methyltransferase activity	4.0901595540349	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01958090893547	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.59156540645412	bayes_pls_golite062009
tRNA methyltransferase activity	2.52700462137917	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.29844424181442	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
rRNA methyltransferase activity	1.86192852581774	bayes_pls_golite062009
transferase activity	1.84002196534744	bayes_pls_golite062009
catalytic activity	1.16774040077235	bayes_pls_golite062009
N-methyltransferase activity	0.0655574594365502	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: