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View Structure Prediction Details

Protein: NIT2_MOUSE
Organism: Mus musculus
Length: 276 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIT2_MOUSE.

Description E-value Query
Range		 Subject
Range
NIT2 - nitrilase family, member 2
 313.0 [0..1] [276..1]
NIT2_XENTR - Omega-amidase NIT2 OS=Xenopus tropicalis GN=nit2 PE=2 SV=1
 312.0 [0..1] [275..1]
NIT2_RAT - Omega-amidase NIT2 OS=Rattus norvegicus GN=Nit2 PE=1 SV=1
 311.0 [0..1] [276..1]
gi|109032725 - gi|109032725|ref|XP_001091514.1| PREDICTED: similar to nitrilase family, member 2 [Macaca mulatta]
 310.0 [0..1] [276..51]
NIT2B_XENLA - Omega-amidase NIT2-B OS=Xenopus laevis GN=nit2b PE=2 SV=1
 306.0 [0..1] [275..1]
gi|47214136 - gi|47214136|emb|CAG01394.1| unnamed protein product [Tetraodon nigroviridis]
 306.0 [0..2] [271..430]
NIT2_BOVIN - Omega-amidase NIT2 OS=Bos taurus GN=NIT2 PE=2 SV=1
 304.0 [0..1] [275..1]
gi|114588194 - gi|114588194|ref|XP_526254.2| PREDICTED: similar to Nitrilase family, member 2 [Pan troglodytes]
 304.0 [0..4] [276..139]

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Predicted Domain #1
Region A:
Residues: [1-276] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTFRLALIQ LQVSSIKSDN LTRACSLVRE AAKQGANIVS LPECFNSPYG TTYFPDYAEK  60
   61 IPGESTQKLS EVAKESSIYL IGGSIPEEDA GKLYNTCSVF GPDGSLLVKH RKIHLFDIDV 120
  121 PGKITFQESK TLSPGDSFST FDTPYCKVGL GICYDMRFAE LAQIYAQRGC QLLVYPGAFN 180
  181 LTTGPAHWEL LQRARAVDNQ VYVATASPAR DDKASYVAWG HSTVVDPWGQ VLTKAGTEET 240
  241 ILYSDIDLKK LAEIRQQIPI LKQKRADLYT VESKKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.30103
Match: 1f89A
Description: hypothetical protein yl85
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.64442398754697 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.35962310800332 bayes_pls_golite062009
N-carbamoylputrescine amidase activity 0.749539597459006 bayes_pls_golite062009
hydrolase activity 0.06604196264626 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle