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View Structure Prediction Details

Protein: NEU2_MOUSE
Organism: Mus musculus
Length: 168 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEU2_MOUSE.

Description E-value Query
Range
Subject
Range
NEU2_RAT - Vasopressin-neurophysin 2-copeptin OS=Rattus norvegicus GN=Avp PE=1 SV=1
246.0 [0..1] [168..1]
gi|109092704 - gi|109092704|ref|XP_001115061.1| PREDICTED: arginine vasopressin (neurophysin II, antidiuretic hormo...
243.0 [0..5] [168..1]
gi|30136 - gi|30136|emb|CAA44682.1| vasopressin-neurophysin precursor [Homo sapiens]
241.0 [0..5] [168..1]
NEU2_BOVIN - Vasopressin-neurophysin 2-copeptin OS=Bos taurus GN=AVP PE=1 SV=1
238.0 [0..5] [168..1]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLARMLNTTL SACFLSLLAF SSACYFQNCP RGGKRAISDM ELRQCLPCGP GGKGRCFGPS  60
   61 ICCADELGCF VGTAEALRCQ EENYLPSPCQ SGQKPCGSGG RCAAVGICCS DESCVAEPEC 120
  121 HDGFFRLTRA REPSNATQLD GPARALLLRL VQLAGTRESV DSAKPRVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.09691
Match: 1npoA
Description: Neurophysin II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
vasopressin receptor binding 7.58997550111955 bayes_pls_golite062009
V1A vasopressin receptor binding 7.58997550111955 bayes_pls_golite062009
V1B vasopressin receptor binding 7.58997550111955 bayes_pls_golite062009
V2 vasopressin receptor binding 7.58997550111955 bayes_pls_golite062009
oxytocin receptor binding 6.57567918033019 bayes_pls_golite062009
G-protein-coupled receptor binding 3.5353239449254 bayes_pls_golite062009
hormone activity 2.63860418688669 bayes_pls_golite062009
receptor binding 2.36717691859691 bayes_pls_golite062009
protein binding 1.90482509358938 bayes_pls_golite062009
binding 1.74382916132518 bayes_pls_golite062009
neuropeptide hormone activity 1.73170644837605 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle