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View Structure Prediction Details

Protein: gi|116008046, gi...
Organism: Drosophila melanogaster
Length: 1314 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|116008046, gi....

Description E-value Query
Range
Subject
Range
gi|114687614 - gi|114687614|ref|XP_001138715.1| PREDICTED: X-linked neuroligin 4 isoform 7 [Pan troglodytes]
695.0 [0..35] [990..1]

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Predicted Domain #1
Region A:
Residues: [1-764]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSSQLADSL VIPALQQFNN SSLRSHNVKL HCARMGESQL LLLLRLLLLP TVLISWMHCA  60
   61 GASTADIYKG ARLGHRIVQT RYGRLHGLIL PLDSFRFLRS VEVFLGVPYA TPPTKQNRFS 120
  121 PTRAPAPWDG IRISDKYSPV CPQRLPNIQN ETAALEKMPK GRLEYLKRLL PFLENQSEDC 180
  181 LYLNVFSPVN AGANEKKLPV IVFIHGESFE WSSGNPYDGS VLASYGEVVV VTLNYRLGIL 240
  241 GFLNANPNPH AHARVANYGL MDQMAALHWI QQNIQKFGGD PNSVTLAGHG TGAACINYLM 300
  301 TSPTMVRGLF HRAILMSGSA YSSWALVEDP VLFAIKLAKE VNCTIPDDIN RHHEQIVDCL 360
  361 RDVPLEDLYL ADIQAPNFLT SFGPSVDGVV IRPGHSNLDI DDLMARNSRR SSADSGFQSS 420
  421 AGGGGGQGGG AGGGGGGGSG SSFGGGYFGG SGAGTMNMGG HYDVLFGVVT GESIWRFSAH 480
  481 DIQNGFEGER RDKIIRTYVR NAYNYHLNEI FYTIVNEYTD WDRTSQHPIN TRDTAVAALS 540
  541 DAQFVAPIVR AGDILAANSP PPVSSSSTAG SPGANAAAST SAGSTQPSGR CYFYVFDYQT 600
  601 KDGDYPQRMG TVHGEDLPYI FGAPLVDGFS HFPQNYTKSE TALSEAVMIF WTNFARTGNP 660
  661 NEHHRQDSSL PVSKERNRFR SITWENYDPL HQKYLEIGMK PRIKNHFRAH QLSIWLRLIP 720
  721 ELHRAGMEDV IARHNLFRNH DDMDLYEGPV KPDPFGISTA AGAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 122.0
Match: 1f8uA
Description: Acetylcholinesterase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.18664942536615 bayes_pls_golite062009
binding 0.112743564301567 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [765-991]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSSSSSSSSS RLLLVDEQLM MKKGRGLNGS AYLNGILGVT TVEPNNMYTT CIPIGGNYSS  60
   61 SGGVFAPTTL ANASSDTLAS GFEAAGYAAY STALSVTIAI GCSLLILNVL IFAGVYYQRD 120
  121 KTRLEVKTLQ KQYQQRSLHQ QVPYPPEPIK HAHYHMGHSQ SSANVIVDVE SHQDQAGQAA 180
  181 MLLQAAAAAA AAAANDVKPP PPHICSNTGM QQQQQVGGGS GGALNNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [992-1213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIEGSKVTTD NLGNVTYSTS SKQQQQHQQQ QQQQQREHMQ IKGMTGTQTF GRSGSGSGGG  60
   61 AGGGAGSASG GASVVVSGSS VSYNPGMMTL PKSGGLHHAA TLNYARNTTA LNMSGGGTAL 120
  121 VDSRGNVLLT STAVGPGMAG TGAGGGSSGG GGGGDCMTLP RNLGLAAAGR HNPTTELQQY 180
  181 QQQQQSSKHQ SNGAVLTGMQ SHHIRGPRPP LRTASSTTTN SS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1214-1314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNNSAMGVAV GVGGGVGNML LDQTPSGGSS SSGVSSAPSS SKGHHTHSHS HAAHLVHSHG  60
   61 DGLVLTSASP VGGQQQQHPQ QHQHPQQQQQ VPQAAMDEMR V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle