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View Structure Prediction Details

Protein: COG8
Organism: Homo sapiens
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COG8.

Description E-value Query
Range
Subject
Range
COG8 - component of oligomeric golgi complex 8
0.0 [1..612] [1..612]
gi|34851657, gi|... - ref|XP_214673.2| similar to Conserved oligomeric Golgi complex component 8 [Rattus norvegicus], gi|1...
0.0 [18..608] [24..614]
COG8_MOUSE - Conserved oligomeric Golgi complex subunit 8 OS=Mus musculus GN=Cog8 PE=1 SV=3
0.0 [17..611] [23..625]
gi|73957158 - gi|73957158|ref|XP_546857.2| PREDICTED: similar to component of oligomeric golgi complex 8 isoform 1...
0.0 [1..607] [1..600]
COG8_BOVIN - Conserved oligomeric Golgi complex subunit 8 OS=Bos taurus GN=COG8 PE=2 SV=1
0.0 [1..612] [1..616]
gi|109129042 - gi|109129042|ref|XP_001100394.1| PREDICTED: similar to component of oligomeric golgi complex 8 [Maca...
0.0 [127..612] [2..487]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATAATIPSV ATATAAALGE VEDEGLLASL FRDRFPEAQW RERPDVGRYL RELSGSGLER  60
   61 LRREPERLAE ERAQLLQQTR DLAFANYKTF IRGAECTERI HRLFGDVEAS LGRLLDRLPS 120
  121 FQQSCRNFVK EAEEISSNRR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.791 N/A N/A a.29.2 Bromodomain
View Download 0.760 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.754 N/A N/A a.7.1 Spectrin repeat
View Download 0.704 N/A N/A a.47.2 t-snare proteins
View Download 0.634 N/A N/A a.7.1 Spectrin repeat

Predicted Domain #2
Region A:
Residues: [141-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLTLNRHT EILEILEIPQ LMDTCVRNSY YEEALELAAY VRRLERKYSS IPVIQGIVNE  60
   61 VRQSMQLMLS QLIQQLRTNI QLPACLRVIG YLRRMDVFTE AELRVKFLQA RDAWLRSILT 120
  121 AIPNDDPYFH ITKTIEASRV HLFDIITQYR AIFSDEDPLL PPAMGEHTVN ESAIFHGWVL 180
  181 QKVSQFLQVL ETDLYRGIGG HLDSLLGQCM YFGLSFSRVG ADFRGQLAPV FQRVAISTFQ 240
  241 KAIQETVEKF QEEMNSYMLI SA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.37
Match: 2d2sA
Description: Crystal Structure of the Exo84p C-terminal Domains
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [403-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAILGTSNMP AAVPATQPGT LQPPMVLLDF PPLACFLNNI LVAFNDLRLC CPVALAQDVT  60
   61 GALEDALAKV TKIILAFHRA EEAAFSSGEQ ELFVQFCTVF LEDLVPYLNR CLQVLFPPAQ 120
  121 IAQTLGIPPT QLSKYGNLGH VNIGAIQEPL AFILPKRETL FTLDDQALGP ELTAPAPEPP 180
  181 AEEPRLEPAG PACPEGGRAE TQAEPPSVGP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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