YRC Public Data Repository - Protein Structure Prediction

Protein:	ZAP70
Organism:	Homo sapiens
Length:	619 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZAP70.

Description	E-value	Query Range	Subject Range
gi\|114579056 - gi\|114579056\|ref\|XP_515637.2\| PREDICTED: zeta-chain associated protein kinase 70kDa [Pan troglodytes...	452.0	[0..1]	[619..1]
gi\|346421 - gi\|346421\|pir\|\|A44266 protein-tyrosine kinase (EC 2.7.1.112) ZAP-70 - human	451.0	[0..1]	[619..1]
gi\|109103908 - gi\|109103908\|ref\|XP_001101570.1\| PREDICTED: zeta-chain associated protein kinase 70kDa isoform 3 [Ma...	446.0	[0..1]	[619..1]
ZAP70_MOUSE - Tyrosine-protein kinase ZAP-70 OS=Mus musculus GN=Zap70 PE=1 SV=3	444.0	[0..1]	[619..1]
gi\|546693 - gi\|546693\|gb\|AAB30743.1\| ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase ...	441.0	[0..1]	[619..1]
gi\|76628669 - gi\|76628669\|ref\|XP_870655.1\| PREDICTED: similar to zeta-chain (TCR) associated protein kinase isofor...	439.0	[0..1]	[618..1]
gi\|58865580, gi\|... - gi\|58865580\|ref\|NP_001012002.1\| zeta-chain (TCR) associated protein kinase [Rattus norvegicus], gi\|5...	438.0	[0..1]	[619..1]

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Predicted Domain #1

Region A:
Residues: [1-619]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDPAAHLPF FYGSISRAEA EEHLKLAGMA DGLFLLRQCL RSLGGYVLSL VHDVRFHHFP  60
   61 IERQLNGTYA IAGGKAHCGP AELCEFYSRD PDGLPCNLRK PCNRPSGLEP QPGVFDCLRD 120
  121 AMVRDYVRQT WKLEGEALEQ AIISQAPQVE KLIATTAHER MPWYHSSLTR EEAERKLYSG 180
  181 AQTDGKFLLR PRKEQGTYAL SLIYGKTVYH YLISQDKAGK YCIPEGTKFD TLWQLVEYLK 240
  241 LKADGLIYCL KEACPNSSAS NASGAAAPTL PAHPSTLTHP QRRIDTLNSD GYTPEPARIT 300
  301 SPDKPRPMPM DTSVYESPYS DPEELKDKKL FLKRDNLLIA DIELGCGNFG SVRQGVYRMR 360
  361 KKQIDVAIKV LKQGTEKADT EEMMREAQIM HQLDNPYIVR LIGVCQAEAL MLVMEMAGGG 420
  421 PLHKFLVGKR EEIPVSNVAE LLHQVSMGMK YLEEKNFVHR DLAARNVLLV NRHYAKISDF 480
  481 GLSKALGADD SYYTARSAGK WPLKWYAPEC INFRKFSSRS DVWSYGVTMW EALSYGQKPY 540
  541 KKMKGPEVMA FIEQGKRMEC PPECPPELYA LMSDCWIYKW EDRPDFLTVE QRMRACYYSL 600
  601 ASKVEGPPGS TQKAEAACA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	123.0
Match:	2ozoA
Description:	No description for 2ozoA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits