YRC Public Data Repository - Protein Structure Prediction

Protein:	COG6
Organism:	Homo sapiens
Length:	657 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COG6.

Description	E-value	Query Range	Subject Range
gi\|26327073, gi\|... - gi\|74142273\|dbj\|BAE31900.1\| unnamed protein product [Mus musculus], gi\|26327073\|dbj\|BAC27280.1\| unna...	0.0	[1..657]	[1..657]
gi\|114651338 - gi\|114651338\|ref\|XP_509639.2\| PREDICTED: component of oligomeric golgi complex 6 isoform 2 [Pan trog... sp\|Q9Y2V7\|COG6_H... - Conserved oligomeric Golgi complex subunit 6 OS=Homo sapiens GN=COG6 PE=1 SV=2 VAR_048760, Conserved...	0.0	[1..657]	[1..657]
gi\|73993301 - gi\|73993301\|ref\|XP_534488.2\| PREDICTED: similar to component of oligomeric golgi complex 6 [Canis fa...	0.0	[1..657]	[1..657]
COG6_RAT - Conserved oligomeric Golgi complex subunit 6 OS=Rattus norvegicus GN=Cog6 PE=2 SV=1	0.0	[1..657]	[1..657]
gi\|109120537 - gi\|109120537\|ref\|XP_001088372.1\| PREDICTED: similar to component of oligomeric golgi complex 6 isofo...	0.0	[1..657]	[1..657]
COG6_BOVIN - Conserved oligomeric Golgi complex subunit 6 OS=Bos taurus GN=COG6 PE=2 SV=1	0.0	[1..657]	[1..657]
gi\|50949900 - gi\|50949900\|emb\|CAH10495.1\| hypothetical protein [Homo sapiens]	0.0	[1..657]	[1..657]
gi\|49522362, gi\|... - gi\|54262226\|ref\|NP_001005812.1\| component of oligomeric golgi complex 6 [Xenopus (Silurana) tropical...	0.0	[16..657]	[1..648]

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Predicted Domain #1

Region A:
Residues: [1-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGSGEVVA VSATGAANGL NNGAGGTSAT TCNPLSRKLH KILETRLDND KEMLEALKAL  60
   61 STFFVENSLR TRRNLRGDIE RKSLAI

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.04
Match:	1x79B
Description:	Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [87-657]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEEFVSIFKE VKEELESISE DVQAMSNCCQ DMTSRLQAAK EQTQDLIVKT TKLQSESQKL  60
   61 EIRAQVADAF LSKFQLTSDE MSLLRGTREG PITEDFFKAL GRVKQIHNDV KVLLRTNQQT 120
  121 AGLEIMEQMA LLQETAYERL YRWAQSECRT LTQESCDVSP VLTQAMEALQ DRPVLYKYTL 180
  181 DEFGTARRST VVRGFIDALT RGGPGGTPRP IEMHSHDPLR YVGDMLAWLH QATASEKEHL 240
  241 EALLKHVTTQ GVEENIQEVV GHITEGVCRP LKVRIEQVIV AEPGAVLLYK ISNLLKFYHH 300
  301 TISGIVGNSA TALLTTIEEM HLLSKKIFFN SLSLHASKLM DKVELPPPDL GPSSALNQTL 360
  361 MLLREVLASH DSSVVPLDAR QADFVQVLSC VLDPLLQMCT VSASNLGTAD MATFMVNSLY 420
  421 MMKTTLALFE FTDRRLEMLQ FQIEAHLDTL INEQASYVLT RVGLSYIYNT VQQHKPEQGS 480
  481 LANMPNLDSV TLKAAMVQFD RYLSAPDNLL IPQLNFLLSA TVKEQIVKQS TELVCRAYGE 540
  541 VYAAVMNPIN EYKDPENILH RSPQQVQTLL S

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.07
Match:	2pftA
Description:	No description for 2pftA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits