YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|28872782, gi\|...
Organism:	Homo sapiens
Length:	587 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|28872782, gi|....

Description	E-value	Query Range	Subject Range
gi\|10436223 - gi\|10436223\|dbj\|BAB14760.1\| unnamed protein product [Homo sapiens]	0.0	[1..587]	[1..587]
gi\|76633250, gi\|... - gi\|76633250\|ref\|XP_872709.1\| PREDICTED: similar to CDK5 regulatory subunit associated protein 1 isof...	0.0	[1..587]	[1..589]
gi\|73992243 - gi\|73992243\|ref\|XP_534385.2\| PREDICTED: similar to CDK5 regulatory subunit associated protein 1 isof...	0.0	[1..587]	[1..583]
CK5P1_MOUSE - CDK5 regulatory subunit-associated protein 1 OS=Mus musculus GN=Cdk5rap1 PE=2 SV=2	0.0	[1..587]	[1..586]
CK5P1_RAT - CDK5 regulatory subunit-associated protein 1 OS=Rattus norvegicus GN=Cdk5rap1 PE=1 SV=1	0.0	[1..587]	[1..584]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA  60
   61 AGPTFQHFLK SASAPQEKLS SEVEDPP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.258	a.5.6	Hypothetical protein MTH1615
View	Download	0.204	a.23.5	Hemolysin expression modulating protein HHA

Predicted Domain #2

Region A:
Residues: [88-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYLMMDELLG RQRKVYLETY GCQMNVNDTE IAWSILQKSG YLRTSNLQEA DVILLVTCSI  60
   61 REKAEQTIWN RLHQLKALKT RRPRSRVPLR IGILGCMAER LKEEILNREK MVDILAGPDA 120
  121 YRDLPRLLAV AESGQQAANV LLSLDETYAD VMPVQT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.02
Match:	1bmtA
Description:	Methionine synthase domain; Methionine synthase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [244-587]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASATSAFVS IMRGCDNMCS YCIVPFTRGR ERSRPIASIL EEVKKLSEQG LKEVTLLGQN  60
   61 VNSFRDNSEV QFNSAVPTNL SRGFTTNYKT KQGGLRFAHL LDQVSRVDPE MRIRFTSPHP 120
  121 KDFPDEVLQL IHERDNICKQ IHLPAQSGSS RVLEAMRRGY SREAYVELVH HIRESIPGVS 180
  181 LSSDFIAGFC GETEEDHVQT VSLLREVQYN MGFLFAYSMR QKTRAYHRLK DDVPEEVKLR 240
  241 RLEELITIFR EEATKANQTS VGCTQLVLVE GLSKRSATDL CGRNDGNLKV IFPDAEMEDV 300
  301 NNPGLRVRAQ PGDYVLVKIT SASSQTLRGH VLCRTTLRDS SAYC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.39794
Match:	2qgqA
Description:	No description for 2qgqA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits