YRC Public Data Repository - Protein Structure Prediction

Protein:	FBXO11
Organism:	Homo sapiens
Length:	843 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBXO11.

Description	E-value	Query Range	Subject Range
gi\|50739002 - gi\|50739002\|ref\|XP_419357.1\| PREDICTED: similar to F-box only protein 11 [Gallus gallus]	0.0	[1..843]	[802..1644]
gi\|56788988 - gi\|56788988\|gb\|AAH88730.1\| Fbxo11 protein [Mus musculus]	0.0	[1..843]	[75..917]
gi\|76629184 - gi\|76629184\|ref\|XP_584914.2\| PREDICTED: similar to F-box only protein 11 [Bos taurus]	0.0	[1..843]	[38..881]
FBX11_RAT - F-box only protein 11 OS=Rattus norvegicus GN=Fbxo11 PE=2 SV=1 tr\|G3H5Q6\|G3H5Q6... - F-box only protein 11 OS=Cricetulus griseus GN=I79_005642 PE=4 SV=1	0.0	[1..843]	[1..843]
gi\|112180697 - gi\|112180697\|gb\|AAH43258.2\| FBXO11 protein [Homo sapiens]	0.0	[1..843]	[73..915]
gi\|49899739, gi\|... - gi\|49899739\|gb\|AAH76869.1\| Fbxo11-prov protein [Xenopus laevis], gi\|148234116\|ref\|NP_001086604.1\| F-...	0.0	[1..843]	[1..843]
gi\|109102880 - gi\|109102880\|ref\|XP_001113723.1\| PREDICTED: similar to F-box only protein 11 isoform 1 isoform 3 [Ma...	0.0	[1..843]	[84..926]

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Predicted Domain #1

Region A:
Residues: [1-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAEESGPGA QNSPYQLRRK TLLPKRTACP TKNSMEGAST STTENFGHRA KRARVSGKSQ  60
   61 DLSAAPAEQY LQEKLPDEVV LKIFSYLLEQ DLCRAACVCK RFSELANDPI LWKRLYMEVF 120
  121 EYTRPMMHPE PGKFYQINPE EYEHPNPWKE SFQQLYKGAH VKPGFAEHFY SNPARYKGRE 180
  181 NMLYYDTIED ALGGVQEAHF DGLIFVHSGI YTDEWIYIES PITMIGAAPG KVADKVIIEN 240
  241 TRDSTFVFME GSEDAYVGYM TIRFNPDDKS AQHHNAHHCL EITVNCSPII DHCIIRSTCT 300
  301 VGSAVCVSGQ GACPTIKHCN ISDCENVGLY ITDHAQGIYE DNEISNNALA GIWVKNHGNP 360
  361 IIRRNHIHHG RDVGVFTFDH GMGYFESCNI H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1p22A
Description:	F-box/WD-repeat protein 1 (beta-TRCP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [392-745]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNRIAGFEVK AYANPTVVRC EIHHGQTGGI YVHEKGRGQF IENKIYANNF AGVWITSNSD  60
   61 PTIRGNSIFN GNQGGVYIFG DGRGLIEGND IYGNALAGIQ IRTNSCPIVR HNKIHDGQHG 120
  121 GIYVHEKGQG VIEENEVYSN TLAGVWVTTG STPVLRRNRI HSGKQVGVYF YDNGHGVLED 180
  181 NDIYNHMYSG VQIRTGSNPK IRRNKIWGGQ NGGILVYNSG LGCIEDNEIF DNAMAGVWIK 240
  241 TDSNPTLRRN KIHDGRDGGI CIFNGGRGLL EENDIFRNAQ AGVLISTNSH PILRKNRIFD 300
  301 GFAAGIEITN HATATLEGNQ IFNNRFGGLF LASGVNVTMK DNKIMNNQDA IEKA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.5
Match:	2inuA
Description:	No description for 2inuA was found.

Predicted Domain #3

Region A:
Residues: [746-843]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSRGQCLYKI SSYTSYPMHD FYRCHTCNTT DRNAICVNCI KKCHQGHDVE FIRHDRFFCD  60
   61 CGAGTLSNPC TLAGEPTHDT DTLYDSAPPI ESNTLQHN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits