YRC Public Data Repository - Protein Structure Prediction

Protein:	PIGS
Organism:	Homo sapiens
Length:	555 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIGS.

Description	E-value	Query Range	Subject Range
gi\|109113738 - gi\|109113738\|ref\|XP_001107461.1\| PREDICTED: similar to phosphatidylinositol glycan class S isoform 2...	0.0	[1..555]	[1..555]
gi\|114668496 - gi\|114668496\|ref\|XP_511797.2\| PREDICTED: phosphatidylinositol glycan anchor biosynthesis, class S is...	0.0	[1..555]	[1..555]
gi\|22761511 - gi\|22761511\|dbj\|BAC11615.1\| unnamed protein product [Homo sapiens]	0.0	[1..555]	[1..555]
PIGS_RAT - GPI transamidase component PIG-S OS=Rattus norvegicus GN=Pigs PE=2 SV=3	0.0	[1..555]	[1..555]
PIGS_BOVIN - GPI transamidase component PIG-S OS=Bos taurus GN=PIGS PE=2 SV=3	0.0	[1..555]	[1..555]
PIGS_MOUSE - GPI transamidase component PIG-S OS=Mus musculus GN=Pigs PE=1 SV=3	0.0	[1..555]	[1..555]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAGAAATH LEVARGKRAA LFFAAVAIVL GLPLWWKTTE TYRASLPYSQ ISGLNALQLR  60
   61 LMVPVTVVFT RESVPLDDQE KLPFTVVHER EIPLKYKMKI KCRFQKAYRR ALDHEEEALS 120
  121 SGSVQEAEAM LDEPQEQAEG SLTVYVISEH SSLLPQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [157-398]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMMSYIGPKR TAVVRGIMHR EAFNIIGRRI VQVAQAMSLT EDVLAAALAD HLPEDKWSAE  60
   61 KRRPLKSSLG YEITFSLLNP DPKSHDVYWD IEGAVRRYVQ PFLNALGAAG NFSVDSQILY 120
  121 YAMLGVNPRF DSASSSYYLD MHSLPHVINP VESRLGSSAA SLYPVLNFLL YVPELAHSPL 180
  181 YIQDKDGAPV ATNAFHSPRW GGIMVYNVDS KTYNASVLPV RVEVDMVRVM EVFLAQLRLL 240
  241 FG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [399-555]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAQPQLPPKC LLSGPTSEGL MTWELDRLLW ARSVENLATA TTTLTSLAQL LGKISNIVIK  60
   61 DDVASEVYKA VAAVQKSAEE LASGHLASAF VASQEAVTSS ELAFFDPSLL HLLYFPDDQK 120
  121 FAIYIPLFLP MAVPILLSLV KIFLETRKSW RKPEKTD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.885	N/A	N/A	a.24.3	Cytochromes

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits