YRC Public Data Repository - Protein Structure Prediction

Protein:	ORC5L
Organism:	Homo sapiens
Length:	435 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORC5L.

Description	E-value	Query Range	Subject Range
ORC5_MOUSE - Origin recognition complex subunit 5 OS=Mus musculus GN=Orc5 PE=2 SV=1	0.0	[1..435]	[1..435]
gi\|56788790, gi\|... - gi\|62079099\|ref\|NP_001014208.1\| origin recognition complex, subunit 5-like [Rattus norvegicus], gi\|5...	0.0	[1..435]	[1..435]
gi\|64174879, gi\|... - gi\|71610986\|dbj\|BAE16572.1\| Origin Recognition Complex subunit 5 [Cricetulus griseus], gi\|64174879\|g...	0.0	[1..435]	[1..435]
gi\|109067761 - gi\|109067761\|ref\|XP_001085300.1\| PREDICTED: similar to origin recognition complex subunit 5 isoform ...	0.0	[1..435]	[113..547]
gi\|114615275 - gi\|114615275\|ref\|XP_519292.2\| PREDICTED: origin recognition complex subunit 5 [Pan troglodytes]	0.0	[1..435]	[159..593]
gi\|73981959 - gi\|73981959\|ref\|XP_852382.1\| PREDICTED: similar to origin recognition complex subunit 5 isoform 1 [C...	0.0	[1..435]	[173..607]
gi\|62898283 - gi\|62898283\|dbj\|BAD97081.1\| origin recognition complex subunit 5 isoform 1 variant [Homo sapiens]	0.0	[1..435]	[1..435]
gi\|71897011, gi\|... - gi\|71897011\|ref\|NP_001025900.1\| origin recognition complex subunit 5 [Gallus gallus], gi\|60098949\|em...	1.0E-99	[8..435]	[21..447]
gi\|47085993, gi\|... - gi\|94733092\|emb\|CAK11285.1\| novel protein similar to vertebrate origin recognition complex, subunit ...	4.0E-97	[1..435]	[15..444]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHLENVVLC RESQVSILQS LFGERHHFSF PSIFIYGHTA SGKTYVTQTL LKTLELPHVF  60
   61 VNCVECFTLR LLLEQILNKL NHLSSSEDGC STEITCETFN DFVRLFKQVT TAENLKDQTV 120
  121 YIVLDKAEYL RDMEANLLPG FLRLQELADR NVTVLFLSEI VWEKFRPNTG CFEPFVLYFP 180
  181 DYSIGNLQKI LSHDHPPEYS ADFYAAYINI LLGVFYTVCR DLKELRHLAV LNFPKYCEPV 240
  241 VKGEASERDT RKLWRNIEPH LKKAMQTVYL REISSSQWEK LQKDDTDPGQ LKGLSAHT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.39794
Match:	1oz4A
Description:	VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [299-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVELPYYSKF ILIAAYLASY NPARTDKRFF LKHHGKIKKT NFLKKHEKTS NHLLGPKPFP  60
   61 LDRLLAILYS IVDSRVAPTA NIFSQITSLV TLQLLTLVGH DDQLDGPKYK CTVSLDFIRA 120
  121 IARTVNFDII KYLYDFL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits