YRC Public Data Repository - Protein Structure Prediction

Protein:	SPC25
Organism:	Homo sapiens
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPC25.

Description	E-value	Query Range	Subject Range
gi\|74004817 - gi\|74004817\|ref\|XP_545510.2\| PREDICTED: similar to spindle pole body component 25 [Canis familiaris]	1.0E-52	[1..224]	[169..394]
gi\|114581551 - gi\|114581551\|ref\|XP_001155607.1\| PREDICTED: similar to Spindle pole body component 25 homolog (S. ce...	1.0E-52	[1..223]	[52..274]
SPC25_RAT - Kinetochore protein Spc25 OS=Rattus norvegicus GN=Spc25 PE=2 SV=1	1.0E-46	[1..224]	[1..226]
SPC25_BOVIN - Kinetochore protein Spc25 OS=Bos taurus GN=SPC25 PE=2 SV=1	3.0E-45	[1..224]	[1..226]
SPC25_MOUSE - Kinetochore protein Spc25 OS=Mus musculus GN=Spc25 PE=2 SV=1 gi\|51859229 - gb\|AAH82117.1\| MGC97939 protein [Xenopus laevis]	1.0E-44	[1..224]	[1..226]
gi\|20160931, gi\|... - gi\|34906038\|ref\|NP_914366.1\| P0518C01.32 [Oryza sativa (japonica cultivar-group)], gi\|20160931\|dbj\|B...	2.0E-42	[2..224]	[18..246]
gi\|42545321, gi\|... - gi\|46109312\|ref\|XP_381714.1\| hypothetical protein FG01538.1 [Gibberella zeae PH-1], gi\|42545321\|gb\|E...	3.0E-37	[2..221]	[24..246]
gi\|50949059 - gi\|50949059\|ref\|XP_493887.1\| hypothetical protein [Oryza sativa] gi\|14719337 - gi\|14719337\|gb\|AAK73155.1\|AC079022_28 hypothetical protein [Oryza sativa]	7.0E-36	[2..222]	[70..306]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEDELALFD KSINEFWNKF KSTDTSCQMA GLRDTYKDSI KAFAEKLSVK LKEEERMVEM  60
   61 FLEYQNQISR QNKLIQEKKD NLLKLIAEVK GKKQELEVLT ANIQDLKEEY SRKKETISTA 120
  121 NKANAERLKR LQKSADLYKD RLGLEIRKIY GEKLQFIFTN IDPKNPESPF MFSLHLNEAR 180
  181 DYEVSDSAPH LEGLAEFQEN VRKTNNFSAF LANVRKAFTA TVYN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1y1uA
Description:	Structure of unphosphorylated STAT5a
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits